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Endoscopic-Ultrasound-Guided Gallbladder Drainage: Potential Shift in Practice or Still a Secondary Option?
Journal article   Open access   Peer reviewed

Endoscopic-Ultrasound-Guided Gallbladder Drainage: Potential Shift in Practice or Still a Secondary Option?

Abdullah A Abbasi, Saurabh Chandan, Sagar Pathak, Dennis Yang and Mustafa A Arain
Current Treatment Options in Gastroenterology, Vol.23, 12
07/09/2025
DOI: 10.1007/s11938-025-00477-5
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CC BY-NC-ND V4.0 Open Access

Abstract

Purpose of Review Endoscopic Ultrasound guided Gall Bladder drainage (EUS-GBD) is a useful tool in management of various gall bladder related pathologies. While the initial use was limited for non-surgical patients with acute cholecystitis, recent data has shown ever expanding indications. The purpose of this review article is to explore recent literature behind EUS-GBD and its role in treatment algorithm of various conditions. Recent Findings In non-surgical candidates with acute cholecystitis, EUS-GBD has better clinical efficacy and safety profile compared with endoscopic trans-papillary gallbladder drainage (ETP-GBD) or percutaneous cholecystostomy tube placement for gallbladder drainage (PCT-GBD). There is increasing evidence that EUS-GBD can be a suitable option for patients’ acute cholecystitis who are candidates for interval cholecystectomy. While there is promising data for use of EUS-GBD for malignant bile duct obstruction (MBDO) in patent cystic duct, its true utility is yet to be seen. Case series and animal studies show future promises of EUS-GBD for cholecystolithotomy and gall bladder polyp resection. Summary Endoscopic Ultrasound guided Gall Bladder drainage (EUS-GBD) is safe and effective options for non-surgical patients with acute cholecystitis. Based on local expertise and case, it can be considered for MBDO or acute cholecystitis patients who are candidates for interval cholecystectomy.

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