Journal article
Endovascular Therapy in Patients With Acute Ischemic Stroke With Large Infarct: A Guideline From the Society of Vascular and Interventional Neurology
Stroke: vascular and interventional neurology, Vol.5(2), e001581
03/01/2025
DOI: 10.1161/SVIN.124.001581
PMCID: PMC12671639
PMID: 41573174
Abstract
BackgroundRecent randomized clinical trials of endovascular therapy in patients with large infarct provided new evidence in support of endovascular interventions in patients with acute ischemic stroke. The Society of Vascular and Interventional Neurology Guidelines and Practice Standards committee aims to provide up‐to‐date recommendations on focused relevant clinical questions. Here, we review current evidence and provide recommendations for the selection and endovascular treatment of patients with anterior circulation large vessel occlusion and large infarct.MethodsThe Society of Vascular and Interventional Neurology Guidelines and Practice Standards committee assembled a writing group and recruited interdisciplinary experts to review and evaluate the current literature. Recommendations were assigned using the Guidelines and Practice Standards Class of Recommendation/Level of Evidence algorithm and guideline format. The recommendations were developed through a consensus process involving an expert panel of vascular neurologists, neurointensivists, and neurointerventionalists. The final guideline was approved by the Guidelines and Practice Standards committee and the Society of Vascular and Interventional Neurology board of directors.ResultsLiterature review yielded 6 high‐quality randomized trials and 6 meta‐analyses of patients with large infarct from anterior circulation large vessel occlusion treated with endovascular therapy versus medical management that have been extracted to derive the enclosed summary recommendations. We provide separate recommendations for those presenting within 6 hours of symptoms onset and those presenting in the 6–24‐hour treatment window.ConclusionThese guidelines provide focused practical recommendations based on recent evidence regarding the selection and endovascular therapy in patients with acute ischemic stroke with large infarct.
Details
- Title: Subtitle
- Endovascular Therapy in Patients With Acute Ischemic Stroke With Large Infarct: A Guideline From the Society of Vascular and Interventional Neurology
- Creators
- Maxim Mokin - University of South FloridaTudor Jovin - Cooper University Health CareSunil Sheth - The University of Texas Health Science Center at HoustonThanh Nguyen - Boston Medical CenterKaiz Asif - University of Illinois ChicagoAmeer Hassan - Valley Baptist Medical CenterAshutosh Jadhav - Barrow Neurological InstituteCynthia Kenmuir - University of PittsburghDavid Liebeskind - UCLA HealthOssama Mansour - Alexandria UniversityRaul Nogueira - University of PittsburghRobin Novakovic - The University of Texas Southwestern Medical CenterSantiago Ortega-Gutierrez - University of IowaAlbert YooWaldo Guerrero - University of South FloridaAmer Malik - University of Miami
- Resource Type
- Journal article
- Publication Details
- Stroke: vascular and interventional neurology, Vol.5(2), e001581
- DOI
- 10.1161/SVIN.124.001581
- PMID
- 41573174
- PMCID
- PMC12671639
- NLM abbreviation
- Stroke Vasc Interv Neurol
- ISSN
- 2694-5746
- eISSN
- 2694-5746
- Publisher
- Wiley Subscription Services, Inc
- Language
- English
- Date published
- 03/01/2025
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984797930802771
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