Journal article
Endovascular Therapy or Childhood Ischemic Stroke
The American journal of case reports, Vol.22(1), pp.1-5
01/05/2021
DOI: 10.12659/AJCR.926529
PMCID: PMC7797604
PMID: 33397839
Abstract
Objective: Rare disease
Background: Ischemic stroke can have a tremendously negative impact on the fitness and well-being of a child. Because endovascular interventions may be of benefit in the adult stroke population, many investigators have recently evaluated the safety and benefits of pharmacological and non-pharmacological options in the pediatric stroke population and compared pediatric patients to their adult counterparts. Some of these trials have had promising results, showing the positive effects of endovascular treatment in children with arterial acute ischemic stroke due to large-vessel occlusion (LVO). The 2015 American Heart Association/American Stroke Association guidelines suggest that mechanical thrombectomy with stent retrievers may be a consideration in some patients who are younger than 18 years and have severe LVO, when treatment (groin puncture) is initiated within 6 h of symptom onset. However, the method remains under-studied in this age group.
Case Report: A 7-year-old girl presented with migraine-like headache, right arm and facial weakness, and expressive aphasia 9.5 h after symptom onset. Her PEDS-NIH stroke scale score was 4. Upon further investigations, she was found to have a left middle cerebral artery cryptogenic stroke with a distal left M1 clot, which was successfully treated with mechanical thrombectomy. Huge improvement was noticed during her subsequent physical examination.
Conclusions: Endovascular therapy offers an exciting treatment option for the management of pediatric stroke. The extent of safety of mechanical thrombectomy among children who present with large-vessel occlusion over an extended time window remains unknown and warrants further investigations.
Details
- Title: Subtitle
- Endovascular Therapy or Childhood Ischemic Stroke
- Creators
- Malik Ghannam - University of MinnesotaLara Zakarna - An-Najah National UniversityIssa Alawneh - University of TorontoMustafa Al-Chalabi - University of ToledoDaniel Kenney-Jung - University of Minnesota
- Resource Type
- Journal article
- Publication Details
- The American journal of case reports, Vol.22(1), pp.1-5
- Publisher
- Int Scientific Information, Inc
- DOI
- 10.12659/AJCR.926529
- PMID
- 33397839
- PMCID
- PMC7797604
- ISSN
- 1941-5923
- eISSN
- 1941-5923
- Number of pages
- 5
- Language
- English
- Date published
- 01/05/2021
- Academic Unit
- Neurology
- Record Identifier
- 9984585319102771
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