Endovascular Treatment of Intracranial Aneurysms

Christopher J Moran; Dewitte T Cross  III; Colin P Derdeyn

doi:10.1055/s-2002-36749

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Endovascular Treatment of Intracranial Aneurysms

Journal article

Peer reviewed

Endovascular Treatment of Intracranial Aneurysms

Christopher J Moran, Dewitte T Cross III and Colin P Derdeyn

Seminars in interventional radiology, Vol.19(4), pp.339-376

2002

DOI: 10.1055/s-2002-36749

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Abstract

ABSTRACT An intracranial aneurysm is a benign disorder that causes patients to have neurological deficits or to die. The sequelae develop because aneurysms rupture into the subarachnoid space or compress nervous tissue. Intracranial aneurysms occur in up to 8% of the population, more commonly in women, and the only modifiable risk factor for hemorrhage is cigarette smoking. Treatment is directed at the prevention of rupture or rebleeding and relief of mass effect. Surgical clipping has been the primary treatment, but in the past 6 years, endovascular therapy (Guglielmi detachable coil® [GDC]) has become widely available. Initially GDC treatment was directed at the nonsurgical candidate but recently has begun to compare with surgical clipping as a definitive mode of therapy. The primary consideration for successful GDC treatment of an aneurysm is the relationship of the aneurysm to its parent vessel and any branches. The size of the aneurysm dome in relation to the aneurysm neck, presence of thrombus, and the inflow zone are also significant factors. Coil compaction and aneurysm remnants at its neck are significant problems in GDC treatment. The technique and instruments are constantly improving: development of the remodeling technique; the introduction of softer, stretch-resistant coils; and the use of flexible coronary stents have permitted successful treatment of patients who once would have been considered poor candidates for this mode of therapy. Future development of more compliant balloons, coated coils, and liquid embolics will extend and improve endovascular therapy for patients with intracranial aneurysms.

Intracranial aneurysms

dissecting aneurysm

subarachnoid hemorrhage

endovascular therapy

saccular aneurysm (berry aneurysm)

Guglielmi detachable coil (GDC)

Details

Title: Subtitle: Endovascular Treatment of Intracranial Aneurysms
Creators: Christopher J Moran
Dewitte T Cross III
Colin P Derdeyn
Resource Type: Journal article
Publication Details: Seminars in interventional radiology, Vol.19(4), pp.339-376
DOI: 10.1055/s-2002-36749
ISSN: 0739-9529
eISSN: 1098-8963
Language: English
Date published: 2002
Academic Unit: Radiology; Neurology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984070578802771

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