Endovascular intervention for acute ischemic stroke in light of recent trials

Kenan Alkhalili; Nohra Chalouhi; Stavropoula Tjoumakaris; David Hasan; Robert M Starke; Mario Zanaty; Robert H Rosenwasser; Pascal Jabbour

doi:10.1155/2014/429549

Back

Endovascular intervention for acute ischemic stroke in light of recent trials

Journal article

Open access

Endovascular intervention for acute ischemic stroke in light of recent trials

Kenan Alkhalili, Nohra Chalouhi, Stavropoula Tjoumakaris, David Hasan, Robert M Starke, Mario Zanaty, Robert H Rosenwasser and Pascal Jabbour

TheScientificWorld, Vol.2014, pp.429549-7

2014

DOI: 10.1155/2014/429549

PMCID: PMC4235257

PMID: 25531001

Files and links (1)

url

https://doi.org/10.1155/2014/429549View

Published (Version of record) Open Access

Abstract

Three recently published trials, MR RESCUE, IMS III, and SYNTHESIS Expansion, evaluating the efficacy and safety of endovascular treatment of acute ischemic stroke have generated concerns about the future of endovascular approach. However, the tremendous evolution that imaging and endovascular treatment modalities have undergone over the past several years has raised doubts about the validity of these trials. In this paper, we review the role of endovascular treatment strategies in acute ischemic stroke and discuss the limitations and shortcomings that prevent generalization of the findings of recent trials. We also provide our experience in endovascular treatment of acute ischemic stroke.

Endovascular Procedures

Clinical Trials as Topic

Stents

Brain Ischemia - therapy

Humans

Stroke - therapy

Details

Title: Subtitle: Endovascular intervention for acute ischemic stroke in light of recent trials
Creators: Kenan Alkhalili - Department of Surgery, University of Arizona, Tucson, AZ Department of Surgery, University of Arizona, Tucson, AZ 85721, USA
Nohra Chalouhi - Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA
Stavropoula Tjoumakaris - Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA
David Hasan - Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, USA
Robert M Starke - Department of Neurosurgery, University of Virginia, Charlottesville, VA 22908, USA
Mario Zanaty - Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA
Robert H Rosenwasser - Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA
Pascal Jabbour - Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA ; Department of Neurological Surgery, Division of Neurovascular Surgery and Endovascular Neurosurgery, Thomas Jefferson University Hospital, 901 Walnut Street, 3rd Floor, Philadelphia, PA 19107, USA
Resource Type: Journal article
Publication Details: TheScientificWorld, Vol.2014, pp.429549-7
DOI: 10.1155/2014/429549
PMID: 25531001
PMCID: PMC4235257
NLM abbreviation: ScientificWorldJournal
ISSN: 2356-6140
eISSN: 1537-744X
Publisher: United States
Language: English
Date published: 2014
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
Record Identifier: 9984040011802771

Metrics

14 Record Views