Journal article
Endovascular treatment of the vertebral artery origin in patients with symptoms of vertebrobasilar ischemia
Neuroradiology, Vol.48(12), pp.917-923
2006
DOI: 10.1007/s00234-006-0151-7
PMID: 17086409
Abstract
Introduction: We report our experience with the endovascular treatment of the vertebral artery origin in patients presenting with symptomatic vertebrobasilar ischemia and compare our results with those reported in the literature.
Methods: In 25 patients, 28 procedures were performed. Patients presented with posterior circulation ischemic symptoms despite optimal medical therapy with antiplatelet drugs and had a digital subtraction angiogram demonstrating stenosis of the origin of the vertebral artery greater than 50%. Retrospective review of the medical records, clinical notes and radiologic-procedural reports was performed.
Results: Of the 25 patients, 18 were male and 7 female. Their ages ranged from 50 to 84 years. In 23 of the 25 patients the contralateral vertebral artery was occluded, hypoplastic, absent, or had greater than 50% stenosis. In 13 of the 25 patients angiographic evidence of significant anterior circulation disease was demonstrated. In 18 of the 25 patients the left vertebral artery was affected. The mean stenosis was 82.6%. Follow-up records were available in 19 patients. The mean follow-up was 24 months. Five of the 19 patients had recurrent symptoms of vertebrobasilar ischemia and three patients were retreated. Of the 28 procedures performed, 23 were angioplasty/stenting and 5 were angioplasties alone. Overall technical success was achieved in 26 of the 28 procedures (92.8%). No procedure-related transient ischemic attack, stroke or death was noted.
Conclusion: Endovascular treatment of the vertebral artery origin in this patient population is feasible, safe, and effective. There are some questions regarding the long-term follow-up and rate of restenosis and clinical recurrences that are yet to be answered.
Details
- Title: Subtitle
- Endovascular treatment of the vertebral artery origin in patients with symptoms of vertebrobasilar ischemia
- Creators
- Guilherme DABUS - Division of Interventional Neuroradiology, Mallinckrodt Institute of Radiology, Barnes-Jewish Hospital, Washington University School of Medicine, P.O. Box 8131, 510 S. Kingshighway Boulevard, St. Louis, MO 63110, United StatesRonald J GERSTLE - Division of Interventional Neuroradiology, Mallinckrodt Institute of Radiology, Barnes-Jewish Hospital, Washington University School of Medicine, P.O. Box 8131, 510 S. Kingshighway Boulevard, St. Louis, MO 63110, United StatesColin P DERDEYN - Division of Interventional Neuroradiology, Mallinckrodt Institute of Radiology, Barnes-Jewish Hospital, Washington University School of Medicine, P.O. Box 8131, 510 S. Kingshighway Boulevard, St. Louis, MO 63110, United StatesDewitte T CROSS - Division of Interventional Neuroradiology, Mallinckrodt Institute of Radiology, Barnes-Jewish Hospital, Washington University School of Medicine, P.O. Box 8131, 510 S. Kingshighway Boulevard, St. Louis, MO 63110, United StatesChristopher J MORAN - Division of Interventional Neuroradiology, Mallinckrodt Institute of Radiology, Barnes-Jewish Hospital, Washington University School of Medicine, P.O. Box 8131, 510 S. Kingshighway Boulevard, St. Louis, MO 63110, United States
- Resource Type
- Journal article
- Publication Details
- Neuroradiology, Vol.48(12), pp.917-923
- Publisher
- Springer; Berlin
- DOI
- 10.1007/s00234-006-0151-7
- PMID
- 17086409
- ISSN
- 0028-3940
- eISSN
- 1432-1920
- Language
- English
- Date published
- 2006
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984014019702771
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