Journal article
Engraftment Syndrome and Acute Graft-versus-Host Disease: A Meta-Analysis
Hawai'i journal of health & social welfare, Vol.79(6), pp.194-201
06/01/2020
PMCID: PMC7281341
PMID: 32524098
Abstract
Engraftment syndrome (ES) has been associated with the surge of neutrophils and cytokines, which is similar to the presumed underlying pathophysiology behind acute graft-versus-host disease (aGVHD). However, there has been no meta-analysis to evaluate the association; therefore, the team attempted to verify an association between ES and aGVHD through meta-analysis. The team searched for titles of articles in MEDLINE (PubMed), the Cochrane Library, and the EMBASE database up until December 2018 that evaluated the association between ES and aGVHD and conducted a random effect meta-analysis of 8 studies involving a total of 1,945 participants to report the pooled odds ratio (OR) for association of ES and aGVHD. The team found a significantly increased odds of developing aGVHD in patients with ES with the pooled OR of 2.76 (95% confidence interval [CI]: 1.64-4.63) and an I
64.5%. In conclusion, patients with ES have significantly higher odds of developing aGVHD compared to patients without ES.
Details
- Title: Subtitle
- Engraftment Syndrome and Acute Graft-versus-Host Disease: A Meta-Analysis
- Creators
- Kittika Poonsombudlert - University of Hawaiʻi at MānoaJakrin Kewcharoen - University of Hawaiʻi at MānoaChattip Prueksapraopong - Navamindradhiraj UniversityNath Limpruttidham - University of Hawaiʻi at Mānoa
- Resource Type
- Journal article
- Publication Details
- Hawai'i journal of health & social welfare, Vol.79(6), pp.194-201
- PMID
- 32524098
- PMCID
- PMC7281341
- ISSN
- 2641-5216
- eISSN
- 2641-5224
- Language
- English
- Date published
- 06/01/2020
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984694748202771
Metrics
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