Journal article
Enlarged cavum septi pellucidi in patients with schizophrenia: clinical and cognitive correlates
The journal of neuropsychiatry and clinical neurosciences, Vol.12(3), pp.344-349
2000
DOI: 10.1176/appi.neuropsych.12.3.344
PMID: 10956567
Abstract
Enlarged cavum septi pellucidi (CSP) is a neurodevelopmental anomaly that has been associated with schizophrenia. This study was designed to evaluate, in patients with schizophrenia, the relationship between the severity of this anomaly and measures of symptom and cognitive skills. Three groups were used: patients with large CSP (n=14), patients without large CSP (n=14), and healthy control subjects (n=14). In patients with large CSP, a significant, inverse relationship was found between size of CSP and measures of cognitive deficit. Thus, the greater the size of the anomaly, the greater the cognitive deficit. No relationship was found between severity of CSP and symptom measures.
Details
- Title: Subtitle
- Enlarged cavum septi pellucidi in patients with schizophrenia: clinical and cognitive correlates
- Creators
- P Nopoulos - Mental Health Clinic Research Centre, University of Iowa College of Medicine, Iowa City 52242, USA. peggy-nopoulos@uiowa.eduA KrieN C Andreasen
- Resource Type
- Journal article
- Publication Details
- The journal of neuropsychiatry and clinical neurosciences, Vol.12(3), pp.344-349
- Publisher
- United States
- DOI
- 10.1176/appi.neuropsych.12.3.344
- PMID
- 10956567
- ISSN
- 0895-0172
- eISSN
- 1545-7222
- Grant note
- MH31593 / NIMH NIH HHS MH40856 / NIMH NIH HHS MH00625 / NIMH NIH HHS
- Language
- English
- Date published
- 2000
- Academic Unit
- Neurology; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984003484402771
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