Journal article
Entamoeba histolytica: a snapshot of current research and methods for genetic analysis
Current opinion in microbiology, Vol.15(4), pp.469-475
08/01/2012
DOI: 10.1016/j.mib.2012.04.011
PMID: 22664276
Abstract
► Entamoeba histolytica is an important human pathogen. ► Recent important research findings are summarized in this article. ► A review of cell biological and molecular tools available is reviewed.
Entamoeba histolytica represents one of the leading causes of parasitic death worldwide. Although identified as the causative agent of amebiasis since 1875, the molecular mechanisms by which the parasite causes disease are still not fully understood. Studying Entamoeba reveals insights into a eukaryotic cell that differs in many ways from better-studied model organisms. Thus, much can be learned from this protozoan parasite on evolution, cell biology, and RNA biology. In this review we discuss selected research highlights in Entamoeba research and focus on the development of molecular biological techniques to study this pathogen. We end by highlighting some of the many questions that remain to be answered in order to fully understand this important human pathogen.
Details
- Title: Subtitle
- Entamoeba histolytica: a snapshot of current research and methods for genetic analysis
- Creators
- Laura Morf - Stanford MedicineUpinder Singh - Stanford University
- Resource Type
- Journal article
- Publication Details
- Current opinion in microbiology, Vol.15(4), pp.469-475
- DOI
- 10.1016/j.mib.2012.04.011
- PMID
- 22664276
- NLM abbreviation
- Curr Opin Microbiol
- ISSN
- 1369-5274
- eISSN
- 1879-0364
- Publisher
- Elsevier Ltd
- Number of pages
- 7
- Language
- English
- Date published
- 08/01/2012
- Academic Unit
- Internal Medicine
- Record Identifier
- 9985244660602771
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