Journal article
Entamoeba stage conversion: progress and new insights
Current opinion in microbiology, Vol.58, pp.62-68
12/01/2020
DOI: 10.1016/j.mib.2020.09.005
PMID: 33032142
Abstract
Entamoeba histolytica, an anaerobic protozoan, is an important global health problem. This parasite has a biphasic life cycle consisting of a dormant cyst stage which is environmentally resistant and transmits the infection, and the proliferative trophozoite stage which is motile and causes invasive disease. The stage conversion process remains poorly understood despite being central to amoebic biology. In this review, we will highlight recent progress in our understanding of Entamoeba stage conversion including dissecting transcriptome analysis in development, characterization of transcriptional networks, demonstration of epigenetic regulation, and role of small molecules that regulate Entamoeba development.
Details
- Title: Subtitle
- Entamoeba stage conversion: progress and new insights
- Creators
- Dipak Manna - Stanford MedicineGretchen M. Ehrenkaufer - Stanford MedicineDaniela Lozano-Amado - Stanford MedicineUpinder Singh - Stanford Medicine
- Resource Type
- Journal article
- Publication Details
- Current opinion in microbiology, Vol.58, pp.62-68
- DOI
- 10.1016/j.mib.2020.09.005
- PMID
- 33032142
- ISSN
- 1369-5274
- eISSN
- 1879-0364
- Publisher
- Current Biology Ltd
- Number of pages
- 7
- Grant note
- 440708 / Consejo Nacional de Ciencia y Tecnologia; Consejo Nacional de Ciencia y Tecnologia (CONACyT) R21-AI119893 / N.I.H.; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Language
- English
- Date published
- 12/01/2020
- Academic Unit
- Internal Medicine
- Record Identifier
- 9985244547802771
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