Journal article
Enzyme activity and behavior in hyperactive children grown up
Biological psychiatry (1969), Vol.24(4), pp.375-383
1988
DOI: 10.1016/0006-3223(88)90173-4
PMID: 3408755
Abstract
Thirty-one men, originally seen as children for problems with overactivity, distractibility, and impulsiveness, were reevaluated at ages 21–23 years. Subjects were interviewed and tested and provided a blood sample for analyses of dopamine-β-hydroxylase (DBH), monoamine oxidase (MAO), and catechol-O-methy-transferase (COMT).
A series of Pearson correlations between the biological variables and psychological measures revealed that MAO levels were negatively associated with measures of drug involvement, cigarette use, fire-setting, and sensation seeking; DBH levels were positively associated with measures of sensation-seeking; and COMT levels were negatively associated with a measure of hostility and positively correlated with a measure of impulsiveness.
Details
- Title: Subtitle
- Enzyme activity and behavior in hyperactive children grown up
- Creators
- Samuel KupermanJohn KramerJan Loney
- Resource Type
- Journal article
- Publication Details
- Biological psychiatry (1969), Vol.24(4), pp.375-383
- Publisher
- Elsevier Inc
- DOI
- 10.1016/0006-3223(88)90173-4
- PMID
- 3408755
- ISSN
- 0006-3223
- eISSN
- 1873-2402
- Language
- English
- Date published
- 1988
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics
- Record Identifier
- 9984003987102771
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