Eosinophilic Sialodochitis Identified in Duct Remnant After Submandibular Gland Resection

Edward Tannenbaum; Claire Orth; Nicole Becker; Henry Hoffman

doi:10.1002/wjo2.70173

Back

Eosinophilic Sialodochitis Identified in Duct Remnant After Submandibular Gland Resection

Journal article

Open access

Peer reviewed

Eosinophilic Sialodochitis Identified in Duct Remnant After Submandibular Gland Resection

Edward Tannenbaum, Claire Orth, Nicole Becker and Henry Hoffman

World journal of otorhinolaryngology - head and neck surgery

09/28/2026

DOI: 10.1002/wjo2.70173

PMID: 42812743

Files and links (1)

url

https://doi.org/10.1002/wjo2.70173View

Published (Version of record) Open Access

Abstract

Eosinophilic sialodochitis (ES) is an increasingly recognized cause of recurrent sialadenitis but likely remains underdiagnosed as it is commonly considered to be nonspecific chronic sialadenitis. ES is likely increasing in prevalence in association with the growing number of allergic diseases and should be considered in patients presenting with multiple episodes of salivary gland pain and swelling refractory to conventional treatment. We highlight this difficulty in diagnosis with a report of ES established following Wharton duct remnant swelling after submandibular gland (SMG) resection for stone removal with photographic, histopathologic, and radiographic analysis. Eosinophilic sialodochitis (ES) is likely underdiagnosed and should be considered in patients with atopy and recurrent salivary gland swelling refractory to standard treatments.Sialolithiasis, Sjögren's syndrome, and IgG4‐related disease are important diagnostic confounders that must be systematically excluded.ES may persist as a ductal disease after gland resection, underscoring the importance of recognizing the duct remnant as a site of recurrence.

Case Study

Details

Title: Subtitle: Eosinophilic Sialodochitis Identified in Duct Remnant After Submandibular Gland Resection
Creators: Edward Tannenbaum - University of Iowa
Claire Orth - University of Iowa
Nicole Becker - University of Iowa
Henry Hoffman - University of Iowa Hospitals and Clinics
Resource Type: Journal article
Publication Details: World journal of otorhinolaryngology - head and neck surgery
DOI: 10.1002/wjo2.70173
PMID: 42812743
ISSN: 2095-8811
eISSN: 2589-1081
Publisher: Chinese Medical Association
Grant note: University of Iowa Hospitals and Clinics, Department of Otolaryngology Head and Neck Surgery Roy J. and Lucille A. Carver College of Medicine, University of Iowa
The authors have nothing to report. Edward Tannenbaum and Claire Orth are supported by the University of Iowa Carver College of Medicine Summer Research Fellowship Program and Department of Otolaryngology.
Language: English
Electronic publication date: 09/28/2026
Academic Unit: Pathology; Radiation Oncology; Otolaryngology
Record Identifier: 9985240903602771

Metrics

1 Record Views