Journal article
Epidemiology of sebaceous carcinoma of the head and neck: implications for lymph node management
Head & neck, Vol.34(12), pp.1765-1768
12/2012
DOI: 10.1002/hed.22009
PMID: 22267270
Abstract
The purpose of this study was to describe the incidence of nodal disease in sebaceous carcinoma and its impact on survival.
Data from the 17 registries of the Surveillance, Epidemiology, and End Results (SEER) database was retrospectively collected for sebaceous carcinoma from 1973 to 2007. Information on location, histologic grade, stage of disease, and survival was gathered.
One thousand eight hundred thirty-six sebaceous carcinomas were diagnosed during the time period: 633 (34.5%) in the eyelid and 786 (42.8%) in the extraocular head and neck skin. Eyelid sebaceous carcinomas had higher histologic grade compared with tumors in extraocular sites (p < .001). Ocular sebaceous carcinomas had a higher incidence of regional or distant metastases at presentation (4.4%) compared with extraocular head and neck sites (0.9%; p = .03). There was a high incidence of N+ disease in poorly differentiated ocular sebaceous carcinomas (15.2%).
The incidence of nodal disease was higher with eyelid tumors. Sentinel lymph node biopsy can be considered for eyelid tumors, but not for non-eyelid head and neck tumors.
Details
- Title: Subtitle
- Epidemiology of sebaceous carcinoma of the head and neck: implications for lymph node management
- Creators
- Geir Tryggvason - Department of Otolaryngology - Head and Neck Surgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, Iowa 52242, USARodrigo BayonNitin A Pagedar
- Resource Type
- Journal article
- Publication Details
- Head & neck, Vol.34(12), pp.1765-1768
- Publisher
- United States
- DOI
- 10.1002/hed.22009
- PMID
- 22267270
- ISSN
- 1043-3074
- eISSN
- 1097-0347
- Language
- English
- Date published
- 12/2012
- Academic Unit
- Otolaryngology
- Record Identifier
- 9984006314902771
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