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Epidural labour analgesia and autism spectrum disorder: is the current evidence sufficient to dismiss an association?
Journal article   Open access   Peer reviewed

Epidural labour analgesia and autism spectrum disorder: is the current evidence sufficient to dismiss an association?

Alexander J Butwick, Daniel A Abrams and Cynthia A Wong
British journal of anaesthesia : BJA, Vol.128(3), pp.393-398
03/2022
DOI: 10.1016/j.bja.2021.12.017
PMCID: PMC10941096
PMID: 35039173
url
https://doi.org/10.1016/j.bja.2021.12.017View
Published (Version of record) Open Access

Abstract

Findings from a population-based study using a sibling-matched analysis published in this issue of the British Journal of Anaesthesia indicate that epidural labour analgesia is not associated with an increased risk of autism spectrum disorder. These findings are consistent with those from three other population-based studies that used similar methodological approaches. Cumulatively, these robust, high-quality epidemiological data support the assertion that there is no meaningful association between epidural labour analgesia and autism spectrum disorder in offspring.
Analgesia, Epidural - adverse effects Analgesia, Obstetrical - adverse effects Analgesics Autism Spectrum Disorder - etiology Female Humans Labor, Obstetric Pregnancy

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