Epstein-Barr virus and Guillain-Barré syndrome

Charles Grose; Paul M Feorino

doi:10.1016/s0140-6736(72)92654-2

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Epstein-Barr virus and Guillain-Barré syndrome

Journal article

Peer reviewed

Epstein-Barr virus and Guillain-Barré syndrome

Charles Grose and Paul M Feorino

The Lancet (British edition), Vol.2(7790), pp.1285-1287

12/16/1972

DOI: 10.1016/s0140-6736(72)92654-2

PMID: 4117812

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Abstract

Five patients with Guillain-Barré (G.B.) syndrome, aged from 18 months to 27 years, had very high levels of antibodies to Epstein-Barr (E.B.) virus. All five had higher titres of E.B.-virus antibody than age-matched control groups. Two of the five patients had infectious mononucleosis (I.M.) but three had neither clinical nor laboratory evidence of this disease. These findings strongly suggest an association of E.B. virus with G.B. syndrome even without the signs of I.M.

Acute Disease

Age Factors

Infectious Mononucleosis - immunology

Spinal Puncture

Humans

Herpesvirus 4, Human - immunology

Antibodies, Heterophile - analysis

Child, Preschool

Infant

Polyradiculopathy - cerebrospinal fluid

Infectious Mononucleosis - diagnosis

Polyradiculopathy - immunology

Antibodies, Viral - analysis

Adolescent

Fluorescent Antibody Technique

Adult

Cerebrospinal Fluid Proteins - analysis

Child

Details

Title: Subtitle: Epstein-Barr virus and Guillain-Barré syndrome
Creators: Charles Grose
Paul M Feorino
Resource Type: Journal article
Publication Details: The Lancet (British edition), Vol.2(7790), pp.1285-1287
DOI: 10.1016/s0140-6736(72)92654-2
PMID: 4117812
ISSN: 0140-6736
eISSN: 1474-547X
Language: English
Date published: 12/16/1972
Academic Unit: Stead Family Department of Pediatrics; Infectious Disease (Pediatrics)
Record Identifier: 9984093327402771

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