Logo image
Erythematous plaques due to platelet plugging: A clue to underlying myeloproliferative disorder
Journal article

Erythematous plaques due to platelet plugging: A clue to underlying myeloproliferative disorder

Mary Seabury Stone, Kristi J. Robson and Warren W. Piette
Journal of the American Academy of Dermatology, Vol.43(2), pp.355-357
08/2000
DOI: 10.1067/mjd.2000.100537
PMID: 10901722

View Online

Abstract

We report a syndrome in a middle-aged woman characterized by tender erythematous plaques with histologic evidence of dramatic dermal vessel occlusion. These cutaneous findings occurred in association with progressive inferior vena cava and portal vein thrombosis while on coumarin anticoagulation, following hepatic transplantation for Budd-Chiari syndrome. The material occluding dermal vessels was proven by immunohistochemical staining to be platelet plugs. These findings led to the diagnosis of an underlying myeloproliferative disorder explaining both her cutaneous and liver abnormalities and institution of appropriate platelet directed anticoagulation with aspirin. (J Am Acad Dermatol 2000;43:355-7.)

Details

Metrics

Logo image