Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty

George R Wandling Jr; Mansi Parikh; Christopher Robinson; Sudeep N Pramanik; Kenneth M Goins; John E Sutphin; Wallace L M Alward; Emily C Greenlee; Young H Kwon; Michael D Wagoner

doi:10.1097/ICO.0b013e3181cc7b02

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Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty

Journal article

Peer reviewed

Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty

George R Wandling Jr, Mansi Parikh, Christopher Robinson, Sudeep N Pramanik, Kenneth M Goins, John E Sutphin, Wallace L M Alward, Emily C Greenlee, Young H Kwon and Michael D Wagoner

Cornea, Vol.29(9), pp.991-995

09/2010

DOI: 10.1097/ICO.0b013e3181cc7b02

PMID: 20520533

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Abstract

To determine the prevalence and risk factors for escalation of glaucoma therapy after deep lamellar endothelial keratoplasty (DLEK). Retrospective review of every case of DLEK performed at a tertiary care facility between December 1, 2003 and January 31, 2006. Eighty eyes met the inclusion criteria. Escalation of glaucoma therapy occurred in 13 eyes (16.3%) during a mean follow-up period of 27.1 months. Ten eyes required additional topical medical therapy, and 3 eyes required surgical intervention. Glaucoma therapy escalation was significantly associated with preexisting glaucoma (42.9% vs. 10.6%; P = 0.008). Escalation of glaucoma therapy is not uncommon after DLEK, especially in eyes with preexisting glaucoma.

Trabeculectomy

Descemet Stripping Endothelial Keratoplasty

Prevalence

Follow-Up Studies

Intraocular Pressure

Graft Rejection - prevention & control

Humans

Middle Aged

Risk Factors

Postoperative Complications - prevention & control

Antihypertensive Agents - administration & dosage

Glaucoma Drainage Implants

Male

Glaucoma - complications

Corneal Diseases - surgery

Aged, 80 and over

Adult

Female

Glaucoma - therapy

Aged

Retrospective Studies

Glaucoma - physiopathology

Corneal Diseases - complications

Details

Title: Subtitle: Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty
Creators: George R Wandling Jr - Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City, USA
Mansi Parikh
Christopher Robinson
Sudeep N Pramanik
Kenneth M Goins
John E Sutphin
Wallace L M Alward
Emily C Greenlee
Young H Kwon
Michael D Wagoner
Resource Type: Journal article
Publication Details: Cornea, Vol.29(9), pp.991-995
Publisher: United States
DOI: 10.1097/ICO.0b013e3181cc7b02
PMID: 20520533
ISSN: 0277-3740
eISSN: 1536-4798
Language: English
Date published: 09/2010
Academic Unit: Ophthalmology and Visual Sciences
Record Identifier: 9983980076102771

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