Journal article
Establishment and characterization of four new human non-small cell lung cancer cell lines
Cancer research (Chicago, Ill.), Vol.44(8), pp.3561-3569
1984
PMID: 6744280
Abstract
Four new human non-small cell lung cancer cell lines have been established in vitro. These cell lines have been characterized by (a) growth of a tumor in nude mice with histopathology similar to that of the primary, (b) isoenzyme patterns phenotypically human and distinct from each other, (c) distinguishing karyotypic findings, (d) growth rate determinations, and (e) presence of epidermal growth factor receptors. Each of the cell lines will form colonies when directly seeded into a flask without soft agar. The development and availability of the four cell lines may facilitate in vitro studies of the biology of this common cancer. Their clonogenic potential may be of value in the study of sensitivity to antineoplastic agents. Their low passage level may mean that their antigens still resemble those of the primary tumor.
Details
- Title: Subtitle
- Establishment and characterization of four new human non-small cell lung cancer cell lines
- Creators
- Pao-Min Loh - Univ. Iowa, coll. medicine, Iowa City IA 52242, United StatesG. H CLAMON - Univ. Iowa, coll. medicine, Iowa City IA 52242, United StatesR. A ROBINSON - Univ. Iowa, coll. medicine, Iowa City IA 52242, United StatesM. L WHITE - Univ. Iowa, coll. medicine, Iowa City IA 52242, United StatesB HUKKU - Univ. Iowa, coll. medicine, Iowa City IA 52242, United StatesN. P ROSSI - Univ. Iowa, coll. medicine, Iowa City IA 52242, United StatesW. D PETERSON - Univ. Iowa, coll. medicine, Iowa City IA 52242, United States
- Resource Type
- Journal article
- Publication Details
- Cancer research (Chicago, Ill.), Vol.44(8), pp.3561-3569
- Publisher
- American Association for Cancer Research; Philadelphia, PA
- PMID
- 6744280
- ISSN
- 0008-5472
- eISSN
- 1538-7445
- Language
- English
- Date published
- 1984
- Academic Unit
- Oral Pathology, Radiology and Medicine; Hematology, Oncology, and Blood & Marrow Transplantation; Pathology; Cardiothoracic Surgery; Internal Medicine
- Record Identifier
- 9984047979202771
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