Logo image
Estimating Premorbid IQ in the Prodromal Phase of a Neurodegenerative Disease
Journal article   Open access   Peer reviewed

Estimating Premorbid IQ in the Prodromal Phase of a Neurodegenerative Disease

Noelle E Carlozzi, Julie C Stout, James A Mills, Kevin Duff, Leigh J Beglinger, Elizabeth H Aylward, Kathryn B Whitlock, Andrea C Solomon, Sarah Queller, Douglas R Langbehn, …
Clinical neuropsychologist, Vol.25(5), pp.757-777
07/01/2011
DOI: 10.1080/13854046.2011.577811
PMCID: PMC3159182
PMID: 21660882
url
https://admin.research-repository.uwa.edu.au/en/publications/7bc97ba7-2137-48f6-8770-94c8e8146010View
Open Access

Abstract

Estimates of premorbid intellect are often used in neuropsychological assessment to make inferences about cognitive decline. To optimize the method of controlling for premorbid intellect in assessments of prodromal neurodegenerative disease, we examined performance on the American National Adult Reading Test (ANART; administered during Years 1 and 3) and the two-subtest version of the Wechsler Abbreviated Scale of Intelligence (WASI; administered in Years 2 and 4) in an ongoing prospective longitudinal study of 371 participants with prodromal Huntington disease and 51 participants with normal CAG repeats. Although both measures performed similarly, the ANART demonstrated slightly lower variability in performance over a 2-year period and had slightly higher test-retest reliability than the WASI.
Prodromal neurodegenerative disease Premorbid IQ Intelligence Neuropsychological assessment Assessment Huntington disease

Details

Metrics

Logo image