Estimation of regional pleural surface expansile forces in intact dogs

E. A Hoffman; T Behrenbeck; P. A Chevalier; E. H Wood

doi:10.1152/jappl.1983.55.3.935

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Estimation of regional pleural surface expansile forces in intact dogs

Journal article

Peer reviewed

Estimation of regional pleural surface expansile forces in intact dogs

E. A Hoffman, T Behrenbeck, P. A Chevalier and E. H Wood

Journal of applied physiology: respiratory, environmental and exercise physiology, Vol.55(3), pp.935-948

1983

DOI: 10.1152/jappl.1983.55.3.935

PMID: 6355027

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Abstract

Distances between percutaneously inserted apical and basal lung markers determined by biplane X-ray, computer-based videometry (J. Appl. Physiol. 34: 544, 1973) were calibrated against dependent percutaneously recorded pleural liquid pressures (J. Appl. Physiol. 31: 277, 1971) in five 10-12 kg mongrel dogs under morphine-pentobarbital anesthesia studied without thoracotomy. At the same apical pleural-liquid pressure values, the apical intermarker distances were uniformly greater when in the head-up rather than head-down position. This finding suggests that the expansile forces acting on the apical regions of the lung, in the head-up position, are greater (-30 ± 2 cmH2O) than would be predicted from 'pleural liquid' pressures (-15 ± 1 cmH2O) measured at this nondependent site in the thorax, and much greater than the 'pleural surface' pressures measured by the generally accepted balloon and counter-pressure techniques. In contrast, in the head-down body position, expansile forces acting on the nondependent basal regions of the lung estimated by the intermarker distance technique were variable to either side of the pressures measured by open-ended liquid-filled catheters, and thus were not significantly different. Mean values measured by the catheters and predicted by the markers were -14 ± 1 and -10 ± 3 cmH2O, respectively.

Air breathing

Biological and medical sciences

Fundamental and applied biological sciences. Psychology

Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics

Vertebrates: respiratory system

Details

Title: Subtitle: Estimation of regional pleural surface expansile forces in intact dogs
Creators: E. A Hoffman - Mayo medical school
T Behrenbeck - Mayo medical school
P. A Chevalier - Mayo medical school
E. H Wood - Mayo medical school
Resource Type: Journal article
Publication Details: Journal of applied physiology: respiratory, environmental and exercise physiology, Vol.55(3), pp.935-948
Publisher: American Physiological Society
DOI: 10.1152/jappl.1983.55.3.935
PMID: 6355027
ISSN: 0161-7567
eISSN: 2691-2465
Language: English
Date published: 1983
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology; Internal Medicine
Record Identifier: 9984318796702771

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