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Evaluating Demographic Representation in Clinical Trials: Use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a Test Case
Journal article   Open access   Peer reviewed

Evaluating Demographic Representation in Clinical Trials: Use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a Test Case

Ana M Ortega-Villa, Noreen A Hynes, Corri B Levine, Katherine Yang, Zanthia Wiley, Nikolaus Jilg, Jing Wang, Jennifer A Whitaker, Christopher J Colombo, Seema U Nayak, …
Open forum infectious diseases, Vol.10(6), ofad290
06/01/2023
DOI: 10.1093/ofid/ofad290
PMCID: PMC10296069
PMID: 37383244
url
https://doi.org/10.1093/ofid/ofad290View
Published (Version of record) Open Access

Abstract

The ability to evaluate representation depends on timely and accurate demographic data within and outside the trial. Surveillance data of hospitalized cases are the best reference comparator during an outbreak as they reflect the population affected and at higher risk of severe disease.
AcademicSubjects ACTT COVID-19 clinical trials Editor's Choice Major MED00290 representation evaluation

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