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Evaluation of Dietary Patterns and All-Cause Mortality: A Systematic Review
Journal article   Open access   Peer reviewed

Evaluation of Dietary Patterns and All-Cause Mortality: A Systematic Review

Laural K English, Jamy D Ard, Regan L Bailey, Marlana Bates, Lydia A Bazzano, Carol J Boushey, Clarissa Brown, Gisela Butera, Emily H Callahan, Janet de Jesus, …
JAMA network open, Vol.4(8), pp.e2122277-e2122277
08/02/2021
DOI: 10.1001/jamanetworkopen.2021.22277
PMCID: PMC8408672
PMID: 34463743
url
https://doi.org/10.1001/jamanetworkopen.2021.22277View
Published (Version of record) Open Access

Abstract

The 2020 Dietary Guidelines Advisory Committee conducted a systematic review of existing research on diet and health to inform the current Dietary Guidelines for Americans. The committee answered this public health question: what is the association between dietary patterns consumed and all-cause mortality (ACM)? To ascertain the association between dietary patterns consumed and ACM. Guided by an analytical framework and predefined inclusion and exclusion criteria developed by the committee, the US Department of Agriculture's Nutrition Evidence Systematic Review (NESR) team searched PubMed, the Cochrane Central Register of Controlled Trials, and Embase and dual-screened the results to identify articles that were published between January 1, 2000, and October 4, 2019. These studies evaluated dietary patterns and ACM in participants aged 2 years and older. The NESR team extracted data from and assessed risk of bias in included studies. Committee members synthesized the evidence, developed conclusion statements, and graded the strength of the evidence supporting the conclusion statements. A total of 1 randomized clinical trial and 152 observational studies were included in the review. Studies enrolled adults and older adults (aged 17-84 years at baseline) from 28 countries with high or very high Human Development Index; 53 studies originated from the US. Most studies were well designed, used rigorous methods, and had low or moderate risks of bias. Precision, directness, and generalizability were demonstrated across the body of evidence. Results across studies were highly consistent. Evidence suggested that dietary patterns in adults and older adults that involved higher consumption of vegetables, fruits, legumes, nuts, whole grains, unsaturated vegetable oils, fish, and lean meat or poultry (when meat was included) were associated with a decreased risk of ACM. These healthy patterns were also relatively low in red and processed meat, high-fat dairy, and refined carbohydrates or sweets. Some of these dietary patterns also included intake of alcoholic beverages in moderation. Results based on additional analyses with confounding factors generally confirmed the robustness of main findings. In this systematic review, consuming a nutrient-dense dietary pattern was associated with reduced risk of death from all causes.
Cause of Death Diet - mortality Diet - standards Diet - statistics & numerical data Diet, Healthy - mortality Diet, Healthy - standards Diet, Healthy - statistics & numerical data Humans Nutrition Policy United States

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