Evaluation of coagulase-negative staphylococci for ability to produce toxic shock syndrome toxin 1

B N Kreiswirth; P M Schlievert; R P Novick

doi:10.1128/JCM.25.10.2028-2029.1987

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Evaluation of coagulase-negative staphylococci for ability to produce toxic shock syndrome toxin 1

Journal article

Open access

Peer reviewed

Evaluation of coagulase-negative staphylococci for ability to produce toxic shock syndrome toxin 1

B N Kreiswirth, P M Schlievert and R P Novick

Journal of clinical microbiology, Vol.25(10), pp.2028-2029

10/1987

DOI: 10.1128/JCM.25.10.2028-2029.1987

PMCID: PMC269397

PMID: 3117846

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Abstract

A large and diverse group of coagulase-negative staphylococci were assayed for the ability to produce toxic shock syndrome toxin 1 (TSST-1) by immunological reactivity, and whole-cell DNAs from 33 of these strains were hybridized with a TSST-1-specific gene probe. None of the strains tested, including isolates that have been reported as TSST-1+, produced the exotoxin, and no DNA homology was found with the gene probe.

Coagulase - metabolism

Staphylococcus aureus - genetics

Enterotoxins - biosynthesis

Enterotoxins - genetics

Nucleic Acid Hybridization

Staphylococcus aureus - enzymology

Bacterial Toxins

Immunodiffusion

Superantigens

DNA, Bacterial - analysis

Sequence Homology, Nucleic Acid

Staphylococcus aureus - metabolism

Details

Title: Subtitle: Evaluation of coagulase-negative staphylococci for ability to produce toxic shock syndrome toxin 1
Creators: B N Kreiswirth - Public Health Research Institute of the City of New York, New York 10016
P M Schlievert
R P Novick
Resource Type: Journal article
Publication Details: Journal of clinical microbiology, Vol.25(10), pp.2028-2029
Publisher: United States
DOI: 10.1128/JCM.25.10.2028-2029.1987
PMID: 3117846
PMCID: PMC269397
ISSN: 0095-1137
eISSN: 1098-660X
Grant note: AI22159 / NIAID NIH HHS
Language: English
Date published: 10/1987
Academic Unit: Microbiology and Immunology; Internal Medicine
Record Identifier: 9984002382202771

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