Journal article
Evaluation of temporal and facial osteomyelitis by simultaneous In-WBC/Tc-99m-MDP bone SPECT scintigraphy and computed tomography scan
Otolaryngology--head and neck surgery, Vol.113(1), pp.36-41
07/1995
DOI: 10.1016/S0194-5998(95)70142-7
PMID: 7603719
Abstract
A reliable imaging technique is needed for follow-up of patients with temporal and facial osteomyelitis. Clinical outcome in 20 patients with suspected osteomyelitis of the temporal/mastoid, calvarium, and mandible facial bones was evaluated with 30 combined In-WBC/Tc-99m MDP bone single photon emission computed tomographic (SPECT) scans and 27 computed tomographic scans. Simultaneous dual-tracer 25-minute SPECT scans were acquired 18 to 20 hours after radiotracer injection by use of a three-detector system. Diagnosis of the 20 patients (age range, 3 to 74 years) included 8 with facial osteomyelitis, 6 with malignant otitis externa, 3 with mandibular osteomyelitis, and 3 with calvarial osteomyelitis. Diagnosis was confirmed by biopsy/culture results in 18 patients and by endoscopic and clinical evaluation in 2 patients with initial negative scans. Of the 30 In-WBC/MDP scans, 15 were true-positive, 13 true-negative, 1 false-negative, and 1 equivocal. Of a total of 27 CT scans, 9 were true-positive, 5 false-negative, and 1 equivocal in patients with biopsy-proven osteomyelitis. Three computed tomographic scans were false-positive and 1 was equivocal in patients without osteomyelitis, because of concurrent postoperative bone abnormalities. Additionally, 8 computed tomographic scans were true-negative. These results suggest that dual In-WBC/Tc-99m MDP bone SPECT scintigraphy provides an accurate imaging modality for diagnosis and follow-up of temporal and facial osteomyelitis when existing clinical or postoperative bone changes make it difficult to detect active osteomyelitis by computed tomographic scan. (OTOLARYNGOL HEAD NECK SURG 1995;113:36-41.)
Details
- Title: Subtitle
- Evaluation of temporal and facial osteomyelitis by simultaneous In-WBC/Tc-99m-MDP bone SPECT scintigraphy and computed tomography scan
- Creators
- PETER C WEBERJAMES E SEABOLDSCOTT M GRAHAMHENRY H HOFFMANNTERESA M SIMONSONBRAD H THOMPSON
- Resource Type
- Journal article
- Publication Details
- Otolaryngology--head and neck surgery, Vol.113(1), pp.36-41
- Publisher
- Mosby, Inc
- DOI
- 10.1016/S0194-5998(95)70142-7
- PMID
- 7603719
- ISSN
- 0194-5998
- eISSN
- 1097-6817
- Language
- English
- Date published
- 07/1995
- Academic Unit
- Radiology; Neurosurgery; Otolaryngology
- Record Identifier
- 9984006308802771
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