Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

John A F Zupancic; Gui-Shuang Ying; Alejandra de Alba Campomanes; Lauren A Tomlinson; Gil Binenbaum; G-ROP Study Group

doi:10.1038/s41372-020-0605-5

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Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

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Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

John A F Zupancic, Gui-Shuang Ying, Alejandra de Alba Campomanes, Lauren A Tomlinson, Gil Binenbaum and G-ROP Study Group

Journal of perinatology, Vol.40(7), pp.1100-1108

07/2020

DOI: 10.1038/s41372-020-0605-5

PMCID: PMC8840947

PMID: 32111976

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https://www.ncbi.nlm.nih.gov/pmc/articles/8840947View

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Abstract

The Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study showed that the addition of postnatal weight gain to birth weight and gestational age detects similar numbers of infants with ROP, but requires examination of fewer infants. To determine the incremental cost-effectiveness of screening with G-ROP compared with conventional screening. We built a microsimulation model of a 1-year US birth cohort <32 weeks gestation, using data from the G-ROP study. We obtained resource utilization estimates from the G-ROP dataset and from secondary sources, and test characteristics from the G-ROP cohort. Among 78,281 infants nationally, screening with G-ROP detected ~25 additional infants with Type 1 ROP. This was accomplished with 36,233 fewer examinations, in 14,073 fewer infants, with annual cost savings of approximately US$2,931,980 through hospital discharge. Screening with G-ROP reduced costs while increasing the detection of ROP compared with current screening guidelines.

Birth Weight

Gestational Age

Humans

Infant

Infant, Newborn

Neonatal Screening

Retinopathy of Prematurity - diagnosis

Retinopathy of Prematurity - epidemiology

Retrospective Studies

Risk Factors

Details

Title: Subtitle: Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study
Creators: John A F Zupancic - Harvard University
Gui-Shuang Ying - Penn Presbyterian Medical Center
Alejandra de Alba Campomanes - University of California, San Francisco
Lauren A Tomlinson - Children's Hospital of Philadelphia
Gil Binenbaum - Penn Presbyterian Medical Center
G-ROP Study Group
Contributors: Jonathan M Klein (Contributor) - University of Iowa, Neonatology
Edward F Bell (Contributor) - University of Iowa, Neonatology
Resource Type: Journal article
Publication Details: Journal of perinatology, Vol.40(7), pp.1100-1108
DOI: 10.1038/s41372-020-0605-5
PMID: 32111976
PMCID: PMC8840947
NLM abbreviation: J Perinatol
ISSN: 0743-8346
eISSN: 1476-5543
Grant note: R01 EY021137 / NEI NIH HHS R01EY021137 / U.S. Department of Health & Human Services | NIH | Office of Extramural Research, National Institutes of Health (OER)
Language: English
Date published: 07/2020
Academic Unit: Stead Family Department of Pediatrics; Neonatology
Record Identifier: 9984353944302771

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