Evaluation of the physicochemical and adhesive properties of an etch-and-rinse adhesive system incorporated with magnesium whitlockite nanoparticles

Francisbênia Alves Silvestre; Davino Machado Andrade Neto; Áldrison Canafístula Rêgo Araújo; Marcos Antonio de Albuquerque Ferreira; Diego Lomonaco Vasconcelos de Oliveira; Sara Jessica Marciano; Adriano Lincoln Albuquerque Mattos; Madiana Magalhães Moreira; Victor Pinheiro Feitosa; Raniel Fernandes Peixoto

doi:10.1016/j.dental.2025.06.002

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Evaluation of the physicochemical and adhesive properties of an etch-and-rinse adhesive system incorporated with magnesium whitlockite nanoparticles

Journal article

Peer reviewed

Evaluation of the physicochemical and adhesive properties of an etch-and-rinse adhesive system incorporated with magnesium whitlockite nanoparticles

Francisbênia Alves Silvestre, Davino Machado Andrade Neto, Áldrison Canafístula Rêgo Araújo, Marcos Antonio de Albuquerque Ferreira, Diego Lomonaco Vasconcelos de Oliveira, Sara Jessica Marciano, Adriano Lincoln Albuquerque Mattos, Madiana Magalhães Moreira, Victor Pinheiro Feitosa and Raniel Fernandes Peixoto

Dental materials, Vol.41(8), pp.938-946

08/2025

DOI: 10.1016/j.dental.2025.06.002

PMID: 40483255

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Abstract

Objective To synthesize and characterize magnesium whitlockite nanoparticles (nMg-WH) to evaluate the physicochemical and adhesive properties of a conventional adhesive incorporating different concentrations of nMg-WH. Method nMg-WH were synthesized using a hydrothermal method and characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and transmission electron microscopy (TEM). Six groups of adhesive systems were prepared with different concentrations of nMg-WH (wt%: 0 % [Control], 0.1 %, 0.2 %, 0.5 %, 1 %, and 2 %) to evaluate the degree of conversion (DC, %), viscosity (cP), water sorption (WS, µg/mm³), and solubility (SL, µg/mm³). Forty-eight molars (n = 8) were sectioned and randomized between groups and evaluated for contact angle (in degrees) and microshear bond strength (µSBS), before and after thermocycling (TC) involving 10,000 cycles with a 30-s immersion time at temperatures of 5 °C and 55 °C. Statistical analysis was performed using one-way ANOVA (DC, cP, WS and SL) or mixed ANOVA (µSBS), followed by Tukey’s test for multiple comparisons (α = 0.05). Results Regarding the physicochemical properties, the 0.2 % (51.3 ± 0.3), 0.5 % (49.0 ± 1.4), and 1 % (49.2 ± 1.9) nMg-WH groups showed significantly higher DC compared to the control (41.0 ± 0.2). The 0.2 % group presented the lowest contact angle (16.24 ± 7.79), indicating enhanced wettability. Viscosity increased proportionally with concentration, although 0.1 % (28.91 ± 0.75) remained comparable (p > 0.05) to the control (31.00 ± 1.08). WS and SL were not significantly affected at higher concentrations (0.5 %, 1 %, and 2 %). Before TC, the 0.1 % (32.1 ± 4.0) and 0.2 % (30.9 ± 2.1) nMg-WH groups demonstrated statistically higher (p < 0.05) µSBS values than the control (18.0 ± 5.2). After TC, concentrations of 0.2–2 % exhibited higher μSBS compared to the control, with the 0.5 % nMg-WH group showing the highest value (31.8 ± 1.0). Significance nMg-WH improved the physicochemical properties of the adhesive system and increased adhesion to dentin, particularly at concentrations ranging from 0.2 % to 1 %.

Dentin-bonding agents

Chemical phenomena

Magnesium whitlockite

Multifunctional nanoparticles

Details

Title: Subtitle: Evaluation of the physicochemical and adhesive properties of an etch-and-rinse adhesive system incorporated with magnesium whitlockite nanoparticles
Creators: Francisbênia Alves Silvestre - Universidade Federal do Ceará
Davino Machado Andrade Neto - Instituto Federal de Educação, Ciência e Tecnologia do Ceará
Áldrison Canafístula Rêgo Araújo - Instituto Federal de Educação, Ciência e Tecnologia do Ceará
Marcos Antonio de Albuquerque Ferreira - Instituto Federal de Educação, Ciência e Tecnologia do Ceará
Diego Lomonaco Vasconcelos de Oliveira - Universidade Federal do Ceará
Sara Jessica Marciano - Universidade Federal do Ceará
Adriano Lincoln Albuquerque Mattos - Embrapa Tropical Agroindustry, Fortaleza, Ceara, Brazil
Madiana Magalhães Moreira - Paulo Picanço School of Dentistry
Victor Pinheiro Feitosa - University of Iowa
Raniel Fernandes Peixoto - Universidade Federal do Ceará
Resource Type: Journal article
Publication Details: Dental materials, Vol.41(8), pp.938-946
DOI: 10.1016/j.dental.2025.06.002
PMID: 40483255
NLM abbreviation: Dent Mater
ISSN: 0109-5641
eISSN: 1879-0097
Publisher: ELSEVIER SCI LTD
Grant note: Fundacao Cearense de Apoio ao Desenvolvimento Cientifico e Tecnologico (FUNCAP): 07874997/2023
The authors acknowledge the Brazilian Nanotechnology National Laboratory (LNNano), part of the National Center for Research in Energy and Materials (CNPEM), for the transmission electron microscopy (TEM) analyses conducted under Proposals 20210560, 20230286, and 20230715. D.M. Andrade Neto acknowledges the financial support provided by the Fundacao Cearense de Apoio ao Desenvolvimento Cientifico e Tecnologico (FUNCAP), under Grant no. 07874997/2023.
Language: English
Electronic publication date: 06/06/2025
Date published: 08/2025
Academic Unit: Operative Dentistry
Record Identifier: 9984829888502771

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