Journal article
Evidence for direct projections from the basal nucleus of the amygdala to retrosplenial cortex in the Macaque monkey
Experimental brain research, Vol.186(1), pp.47-57
03/2008
DOI: 10.1007/s00221-007-1203-x
PMID: 18049816
Abstract
The role of the primate retrosplenial cortex (RSC) in memory processing and spatial navigation has been well established. Recently, processing emotionally salient information has been attributed to the RSC as well. Little anatomical data, however, exist linking the RSC with known emotional processing centers within the brain. The amygdala has been implicated as a substrate for modulating memory for emotionally salient events; yet no study to date has demonstrated that this area has a direct connection in the primate brain. With modern retrograde tracer injections into the RSC and adjacent cortical areas of the monkey (Macaca fascicularis), we demonstrate that there are efferent projections from the basal nucleus of the amygdala to the RSC and area 31. These projections offer anatomical data supporting the hypothesis that the RSC might receive emotionally salient input directly from the amygdala and suggest a role for the RSC as a node within a neural system potentially capable of integrating emotional information for use in memory or other cognitive processes.
Details
- Title: Subtitle
- Evidence for direct projections from the basal nucleus of the amygdala to retrosplenial cortex in the Macaque monkey
- Creators
- J Buckwalter - Center for Autism Research 8110 La Jolla Shores Dr., Suite 201 La Jolla CA 92037 USAC Schumann - Department of Neurosciences University of California at San Diego 9500 Gilman Drive La Jolla CA 92093 USAG Van Hoesen - Departments of Anatomy and Cell Biology and Neurology University of Iowa Iowa City IA 52242 USA
- Resource Type
- Journal article
- Publication Details
- Experimental brain research, Vol.186(1), pp.47-57
- Publisher
- Springer-Verlag; Berlin/Heidelberg
- DOI
- 10.1007/s00221-007-1203-x
- PMID
- 18049816
- ISSN
- 0014-4819
- eISSN
- 1432-1106
- Language
- English
- Date published
- 03/2008
- Academic Unit
- Orthopedics and Rehabilitation
- Record Identifier
- 9984001149402771
Metrics
31 Record Views