Journal article
Evidence for linkage of Charcot-Marie-Tooth neuropathy (CMT1) to apolipoprotein A2 (Apo-A2)
American journal of human genetics, Vol.42(1), pp.74-76
01/01/1988
PMCID: PMC1715300
PMID: 3122561
Abstract
We studied 169 members of 15 families with Charcot-Marie-Tooth neuropathy (CMT1) showing male-to-male transmission and slow motor-nerve conduction velocities. Four of these families were informative for linkage to apolipoprotein A2 on chromosome 1 (1q21-23) with an overall lod score of 2.45 at theta = .001. There was no statistical evidence of genetic heterogeneity.
Details
- Title: Subtitle
- Evidence for linkage of Charcot-Marie-Tooth neuropathy (CMT1) to apolipoprotein A2 (Apo-A2)
- Creators
- Victor Ionasescu - University of IowaRichard Anderson - Department of Pediatrics, University of Iowa Hospitals, Iowa City 52242Trudy L Burns - University of IowaCharles Searby - Department of Pediatrics, University of Iowa Hospitals, Iowa City 52242Rebecca Ionasescu - Department of Pediatrics, University of Iowa Hospitals, Iowa City 52242Robert Ferrell - Department of Pediatrics, University of Iowa Hospitals, Iowa City 52242
- Resource Type
- Journal article
- Publication Details
- American journal of human genetics, Vol.42(1), pp.74-76
- PMID
- 3122561
- PMCID
- PMC1715300
- ISSN
- 0002-9297
- eISSN
- 1537-6605
- Language
- English
- Date published
- 01/01/1988
- Academic Unit
- Stead Family Department of Pediatrics; Epidemiology; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984364396802771
Metrics
8 Record Views