Journal article
Evidence of optic pathway gliomas after previously negative neuroimaging
Ophthalmology (Rochester, Minn.), Vol.104(6), pp.930-935
1997
DOI: 10.1016/S0161-6420(97)30205-X
PMID: 9186431
Abstract
Purpose: The authors emphasize the potential for the development of anterior visual pathway gliomas, evidenced by computed tomography (CT) or magnetic resonance imaging (MRI) scans, in neurofibromatosis type 1 (NF1) patients who previously had normal neuroimaging studies.
Methods: The clinic charts and CT and MRI scans were retrospectively reviewed for all patients evaluated at the neurofibromatosis clinic of one referral center over a period of 7 years. Patients with neuroimaging studies demonstrating anterior visual pathway gliomas who previously had normal scans were identified, and their cases are described in detail. A similar, previously reported series, from the pediatric literature, was also reviewed.
Results: Eight percent (28/360) of patients had CT or MRI scans revealing optic gliomas. Two of these patients had normal neuroimaging studies previously.
Conclusion: A negative neuroimaging study in an NF1 patient does not exclude the future development of an optic glioma.
Details
- Title: Subtitle
- Evidence of optic pathway gliomas after previously negative neuroimaging
- Creators
- Guy G Massry - Department of Ophthalmology, Anheuser-Busch Eye Institute, Saint Louis University Health Sciences Center, St. Louis, Missouri, United StatesCharles F Morgan - Department of Ophthalmology, Anheuser-Busch Eye Institute, Saint Louis University Health Sciences Center, St. Louis, Missouri, United StatesSophia M Chung - Department of Ophthalmology, Anheuser-Busch Eye Institute, Saint Louis University Health Sciences Center, St. Louis, Missouri, United States
- Resource Type
- Journal article
- Publication Details
- Ophthalmology (Rochester, Minn.), Vol.104(6), pp.930-935
- Publisher
- Elsevier
- DOI
- 10.1016/S0161-6420(97)30205-X
- PMID
- 9186431
- ISSN
- 0161-6420
- eISSN
- 1549-4713
- Language
- English
- Date published
- 1997
- Academic Unit
- Neurology; Ophthalmology and Visual Sciences
- Record Identifier
- 9984111972902771
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