Journal article
Evolution of genes and genomes on the Drosophila phylogeny
Nature, Vol.450(7167), pp.203-218
2007
DOI: 10.1038/nature06341
PMID: 17994087
Abstract
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
Details
- Title: Subtitle
- Evolution of genes and genomes on the Drosophila phylogeny
- Creators
- Drosophila Genomes Consortium (Author)Andrew G Clark - Department of Molecular Biology and GeneticsMichael B Eisen - Lawrence Berkeley National Laboratory [Berkeley]Douglas R Smith - Agencourt Bioscience CorporationCasey M Bergman - Faculty of Life ScienceBrian Oliver - Laboratory of Cellular and Developmental BiologyTherese A Markow - Department of Ecology and Evolutionary BiologyThomas C Kaufman - Department of BiologyManolis Kellis - Massachusetts Institute of TechnologyWilliam Gelbart - Harvard University [Cambridge]Venky N Iyer - University of California [Berkeley]Daniel A Pollard - University of California [Berkeley]Timothy B Sackton - Department of Molecular Biology and GeneticsAmanda M Larracuente - Department of Molecular Biology and GeneticsNadia D Singh - Department of Molecular Biology and GeneticsJose P Abad - Centro de Biología Molecular Severo OchoaDawn N Abt - Department of Ecology and Evolutionary BiologyBoris Adryan - Laboratory of Molecular BiologyMontserrat Aguade - Departament de GeneticaHiroshi Akashi - Department of BiologyWyatt W Anderson - Department of GeneticsCharles F Aquadro - Department of Molecular Biology and GeneticsDavid H Ardell - Uppsala UniversityRoman Arguello - Department of Ecology and Evolution [Lausanne]Carlo G Artieri - Department of BiologyDaniel A Barbash - Department of Molecular Biology and GeneticsDaniel Barker - School of BiologyPaolo Barsanti - Università degli Studi di Bari Aldo MoroPhil Batterham - Department of GeneticsSerafim Batzoglou - Stanford University [Stanford]Dave Begun - University of California [Davis]Arjun Bhutkar - Boston University [Boston]Enrico Blanco - Centro de Regulación GenómicaStephanie A Bosak - Agencourt Bioscience CorporationRobert K Bradley - University of California [Berkeley]Adrianne D Brand - Agencourt Bioscience CorporationMichael R Brent - Washington University in Saint LouisAngela N Brooks - University of California [Berkeley]Randall H Brown - Washington University in Saint LouisRoger K Butlin - University of SheffieldCorrado Caggese - Università degli Studi di Bari Aldo MoroBrian R Calvi - Department of BiologyA Bernardo de Carvalho - Universidade Federal Rural do Rio de JaneiroAnat Caspi - Department of BioengineeringSergio Castrezana - Tucson Stock CenterSusan E Celniker - Lawrence Berkeley National Laboratory [Berkeley]Jean L Chang - Massachusetts Institute of TechnologyCharles Chapple - Centro de Regulación GenómicaSourav Chatterji - University of California [Berkeley]Asif Chinwalla - Genome Sequencing CenterAlberto Civetta - University of WinnipegSandra W Clifton - Genome Sequencing CenterJosep M Comeron - Iowa State UniversityJames C Costello - Indiana University [Bloomington]Jerry A Coyne - Department of Ecology and Evolution [Lausanne]Jennifer Daub - The Wellcome Trust Sanger Institute [Cambridge]Robert G David - Agencourt Bioscience CorporationArthur L Delcher - Center for Bioinformatics and Computational BiologyKim Delehaunty - Genome Sequencing CenterChuong B Do - Stanford University [Stanford]Heather Ebling - Agencourt Bioscience CorporationKevin Edwards - Illinois State UniversityThomas Eickbush - Department of BiologyJay D Evans - United States Department of Agriculture - USDA (USA)Alan Filipski - Arizona State University [Tempe]Sven Findeiss - Arizona State University [Tempe]Eva Freyhult - Uppsala UniversityLucinda Fulton - Washington University in Saint LouisRobert Fulton - Washington University in Saint LouisAna C L Garcia - Universidade Federal do Rio Grande do SulAnastasia Gardiner - School of BiologyDavid A Garfield - Department of BiologyBarry E Garvin - Agencourt Bioscience CorporationGreg Gibson - Department of GeneticsDon Gilbert - Department of BiologySante Gnerre - Massachusetts Institute of TechnologyJennifer Godfrey - Genome Sequencing CenterRobert Good - Department of GeneticsValer Gotea - Department of BiologyBrenton Gravely - University of ConnecticutAnthony J Greenberg - Department of Molecular Biology and GeneticsSam Griffiths-Jones - Faculty of Life ScienceSamuel Gross - Computer Science DépartementRoderic Guigo - Centro de Regulación GenómicaErik A Gustafson - Agencourt Bioscience CorporationWilfried Haerty - Mc Master UniversityMatthew W Hahn - Indiana UniversityDaniel L Halligan - Institute of Evolutionary BiologyAaron L Halpern - J. Craig Venter InstituteGillian M Halter - Department of BiologyMira V Han - Indiana University [Bloomington]Andreas Heger - University of Oxford [Oxford]Ladeana Hillier - Washington University in Saint LouisAngie S Hinrichs - Center for Biomolecular Science and EngineeringIan Holmes - Department of BioengineeringRoger A HoskinsMelissa J HubiszDan HultmarkMelanie A HuntleyDavid B Jaffe - Massachusetts Institute of Technology
- Contributors
- Migration ProdInra (Editor)
- Resource Type
- Journal article
- Publication Details
- Nature, Vol.450(7167), pp.203-218
- Publisher
- Nature Publishing Group
- DOI
- 10.1038/nature06341
- PMID
- 17994087
- ISSN
- 0028-0836
- eISSN
- 1476-4679
- Language
- English
- Date published
- 2007
- Academic Unit
- Biology
- Record Identifier
- 9983991961402771
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