Journal article
Evolving challenges to model human diseases for translational research
Cell and tissue research, Vol.380(2), pp.305-311
05/2020
DOI: 10.1007/s00441-019-03134-3
PMID: 32130478
Abstract
Animal models are a significant component of biomedical research and play an important role in translational studies. Traditionally, rodent models have been the mainstay and principal choice of researchers but in recent years, there have been significant changes in the landscape of animal modeling. For example, newer techniques have greatly expanded the use and successful application of large animal models such as pigs for translational studies. The evolving types and species of animal models can influence the research landscape in terms of facilities, expertise, reproducibility and funding streams, which creates new challenges for research studies. It is also important that investigators are prepared to address the necessity of their animal model research and capable to educate the public regarding its value.
Details
- Title: Subtitle
- Evolving challenges to model human diseases for translational research
- Creators
- Amanda P Beck - Albert Einstein College of MedicineDavid K Meyerholz - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Cell and tissue research, Vol.380(2), pp.305-311
- DOI
- 10.1007/s00441-019-03134-3
- PMID
- 32130478
- ISSN
- 0302-766X
- eISSN
- 1432-0878
- Grant note
- P30 DK054759 / NIDDK NIH HHS P01 HL091842 / NHLBI NIH HHS
- Language
- English
- Date published
- 05/2020
- Academic Unit
- Pathology
- Record Identifier
- 9984186636702771
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