Journal article
Ex Vivo Functional Evaluation of Synaptic Transmission from Rods to Rod Bipolar Cells in Mice
Methods in molecular biology (Clifton, N.J.), Vol.1753, pp.203-216
2018
DOI: 10.1007/978-1-4939-7720-8_14
PMCID: PMC6309191
PMID: 29564791
Abstract
Mice have been widely used as a model organism to study mechanisms of phototransduction and synaptic transmission in the retina. Genetic manipulations and electrophysiological techniques for analysis of photoreceptor and rod bipolar cell function in mice are uniquely advanced. Here, we describe a set of biochemical and electrophysiological techniques for evaluation of synaptic transmission at the rod-rod bipolar cell synapse, which represents the first and key step in the processing of dim-light visual information.
Details
- Title: Subtitle
- Ex Vivo Functional Evaluation of Synaptic Transmission from Rods to Rod Bipolar Cells in Mice
- Creators
- Johan Pahlberg - Department of Ophthalmology, Stein Eye Institute, UCLA, Los Angeles, CA, USAAnurima Majumder - Moffitt Cancer Center, Tampa, FL, USANikolai O Artemyev - Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA. nikolai-artemyev@uiowa.edu
- Resource Type
- Journal article
- Publication Details
- Methods in molecular biology (Clifton, N.J.), Vol.1753, pp.203-216
- DOI
- 10.1007/978-1-4939-7720-8_14
- PMID
- 29564791
- PMCID
- PMC6309191
- NLM abbreviation
- Methods Mol Biol
- eISBN
- 9781493977208; 1493977202
- ISSN
- 1064-3745
- eISSN
- 1940-6029
- Publisher
- United States
- Grant note
- R01 EY010843 / NEI NIH HHS R01 EY012682 / NEI NIH HHS
- Language
- English
- Date published
- 2018
- Academic Unit
- Molecular Physiology and Biophysics; Iowa Neuroscience Institute; Ophthalmology and Visual Sciences
- Record Identifier
- 9984070109802771
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