Journal article
Examination of Bilateral Eyeblink Conditioning in Rats
Behavioral neuroscience, Vol.123(6), pp.1346-1352
12/2009
DOI: 10.1037/a0017314
PMCID: PMC2830096
PMID: 20001118
Abstract
This experiment monitored eyelid responses bilaterally during delay eyeblink conditioning in rats. Rats were given paired or unpaired training with a tone or light conditioned stimulus (CS) and a unilateral periorbital shock unconditioned stimulus (US). Rats given paired training acquired high levels of conditioned responses (CRs), which occurred in both eyelids. However, acquisition was faster, and the overall percentage of CRs was greater in the eyelid that was ipsilateral to the US. CRs in the eyelid ipsilateral to the US also had shorter onset latencies and larger amplitudes than CRs in the contralateral eyelid. Both eyelids consistently showed high percentages of unconditioned responses (UR) to the US, and the UR amplitude decreased across training sessions in the paired group. The present study demonstrated that CRs occur robustly in both eyelids of rats given eyeblink conditioning, which is similar to previous findings in humans and monkeys. The results also showed that conditioning occurs more prominently in the eyelid that is ipsilateral to the US, which is similar to previous findings in humans, monkeys, dogs, and rabbits.
Details
- Title: Subtitle
- Examination of Bilateral Eyeblink Conditioning in Rats
- Creators
- Matthew M Campolattaro - Department of Psychology, University of IowaJohn H Freeman - Department of Psychology, University of Iowa
- Resource Type
- Journal article
- Publication Details
- Behavioral neuroscience, Vol.123(6), pp.1346-1352
- DOI
- 10.1037/a0017314
- PMID
- 20001118
- PMCID
- PMC2830096
- NLM abbreviation
- Behav Neurosci
- ISSN
- 0735-7044
- eISSN
- 1939-0084
- Publisher
- American Psychological Association
- Grant note
- DOI: 10.13039/100000025, name: National Institute of Mental Health, award: 080005
- Language
- English
- Date published
- 12/2009
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984065755802771
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