Journal article
Examination of Predictors of Pain at 12 Months Postdiagnosis in Head and Neck Cancer Survivors
Otolaryngology-head and neck surgery, Vol.169(6), pp.1506-1512
12/2023
DOI: 10.1002/ohn.416
PMCID: PMC10766866
PMID: 37403789
Abstract
OBJECTIVE Pain following the completion of treatment is important but has received less attention in the head and neck cancer (HNC) literature. The present study sought to examine the prevalence and predictors of pain measured 12 months postdiagnosis and its impact on HNC-specific health-related quality of life (HRQOL) in 1038 HNC survivors. STUDY DESIGN Prospective observational study. SETTING Single-institution tertiary care center. METHODS Pain was measured using a single item ranging from 0 to 10 with 0 representing no pain and 10 representing the worst pain possible. Self-reported depressive symptomatology was measured using the Beck Depression Inventory and self-reported problem alcohol use was measured by the Short Michigan Alcoholism Screening Test. HNC-specific HRQOL was measured using the Head and Neck Cancer Inventory (HNCI). RESULTS Hierarchical multivariable linear regression analyses indicated that in addition to pain at 3 months postdiagnosis (β = .145, t = 3.18, sr2 = .019, p = .002), both depressive symptomatology (β = .110, t = 2.49, sr2 = .011, p = .015) and problem alcohol use (β = .092, t = 2.07, sr2 = .008, p = .039) were significant predictors of pain at 12 months postdiagnosis. Subgroup analyses suggest that across all 4 HNCI domains, those in the moderate and severe pain groups at 12 months postdiagnosis failed to reach 70 which is indicative of high functioning. CONCLUSION Pain in patients with HNC is a considerable issue at 12 months postdiagnosis, deserving further attention. Behavioral factors such as depression and problem alcohol use may be associated with pain and require systematic screening over time to identify and treat issues that impact optimal long-term recovery from HNC, including disease-specific HRQOL.
Details
- Title: Subtitle
- Examination of Predictors of Pain at 12 Months Postdiagnosis in Head and Neck Cancer Survivors
- Creators
- M Bryant Howren - Florida State UniversityAaron Seaman - University of IowaGrace L Super - Florida State UniversityAlan J Christensen - East Carolina UniversityNitin A Pagedar - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Otolaryngology-head and neck surgery, Vol.169(6), pp.1506-1512
- DOI
- 10.1002/ohn.416
- PMID
- 37403789
- PMCID
- PMC10766866
- NLM abbreviation
- Otolaryngol Head Neck Surg
- eISSN
- 1097-6817
- Language
- English
- Electronic publication date
- 07/05/2023
- Date published
- 12/2023
- Academic Unit
- Psychological and Brain Sciences; Center for Social Science Innovation; General Internal Medicine; Community and Behavioral Health; Otolaryngology; Internal Medicine
- Record Identifier
- 9984442223502771
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