Journal article
Examination of continuum and micro-structural properties of human vertebral cancellous bone using combined cellular solid models
Biomechanics and modeling in mechanobiology, Vol.2(2), pp.97-107
11/2003
DOI: 10.1007/s10237-003-0031-6
PMID: 14586811
Abstract
Two- and three-dimensional structural models of the vertebral body have been used to estimate the mechanical importance of parameters that are difficult to quantify experimentally such as lattice disorder, trabecular thickness, trabecular spacing, connectivity, and fabric. Many of the models that investigate structure-function relationships of the vertebral body focus only on the trabecular architecture and neglect solid-fluid interactions. We developed a cellular solid model composed of two idealized unit cell geometries to investigate the continuum and micro-structural properties of human vertebral cancellous bone in a mathematically tractable model. Using existing histomorphological data we developed structure-function relationships for the mechanical properties of the solid phase, estimated the micro-structural strains, and predicted the fluid flow characteristics. We found that the micro-structural strains may be 1.7 to 2.2 times higher than the continuum level strains between the ages of 40 and 80. In addition, the predicted permeability agrees well with the experimental data.
Details
- Title: Subtitle
- Examination of continuum and micro-structural properties of human vertebral cancellous bone using combined cellular solid models
- Creators
- E A Sander - Department of Biomedical Engineering, Tulane University, New Orleans, LA 70118, USAD A ShimkoK C DeeE A Nauman
- Resource Type
- Journal article
- Publication Details
- Biomechanics and modeling in mechanobiology, Vol.2(2), pp.97-107
- DOI
- 10.1007/s10237-003-0031-6
- PMID
- 14586811
- NLM abbreviation
- Biomech Model Mechanobiol
- ISSN
- 1617-7959
- eISSN
- 1617-7940
- Publisher
- Germany
- Language
- English
- Date published
- 11/2003
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center; Chemical and Biochemical Engineering
- Record Identifier
- 9984064256502771
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