Journal article
Examining Hepatitis, A and B Vaccination, and HBV Reactivation Monitoring During Direct-Acting Antiviral Therapy for Hepatitis C
Journal of community health, Vol.43(6), pp.1124-1127
12/2018
DOI: 10.1007/s10900-018-0530-0
PMID: 29846860
Abstract
The objective of this study was to examine Hepatitis A (HAV) and Hepatitis B (HBV) screening, and the risk of HBV reactivation during Hepatitis C (HCV) therapy with direct-acting antivirals (DAAs). A retrospective chart review was performed of patients treated with second generation DAA therapy from January 2014 to September 2016 at the Iowa City VA Healthcare System. In total 409 patients initiated HCV treatment, 308 (75%) and 241 (59%) were HAV and HBV vaccine eligible, respectively. Among those, 24 (8%) received a HAV vaccine, while only 20 (8%) received a HBV vaccine. Of these, 7 patients initiating an immunization in the clinic had record of completing the series. Further, 101 patients had a reactive Hepatitis B core Antibody indicating previous HBV infection, and 3 of these were tested for HBV reactivation during HCV therapy. Overall, the assessment found low rates of HAV and HBV vaccine administration, indicating missed opportunities for preventative care during HCV therapy. With the known risk of HBV reactivation with DAAs, the need for HAV and HBV screening is essential.
Details
- Title: Subtitle
- Examining Hepatitis, A and B Vaccination, and HBV Reactivation Monitoring During Direct-Acting Antiviral Therapy for Hepatitis C
- Creators
- John Davison - Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA. john-davison@uiowa.eduAmy O'Shea - Comprehensive Access and Delivery Research & Evaluation (CADRE) at the Iowa City Iowa City VA Healthcare System, Iowa City, IA, USANancee Waterbury - Department of Pharmacy, Iowa City VA Healthcare System, Iowa City, IA, USAYolanda Villalvazo - Department of Internal Medicine, Iowa City VA Healthcare System, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Journal of community health, Vol.43(6), pp.1124-1127
- DOI
- 10.1007/s10900-018-0530-0
- PMID
- 29846860
- ISSN
- 0094-5145
- eISSN
- 1573-3610
- Language
- English
- Date published
- 12/2018
- Academic Unit
- Orthopedics and Rehabilitation; Pharmacy Practice and Science; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984094515202771
Metrics
10 Record Views