Journal article
Excised larynx evaluation of wedge-shaped adjustable balloon implant for minimally invasive type I thyroplasty
The Laryngoscope, Vol.124(4), pp.942-949
04/01/2014
DOI: 10.1002/lary.24409
PMCID: PMC4235617
PMID: 24115091
Abstract
Objectives/Hypothesis
To describe the method of inserting a wedge-shaped adjustable balloon implant (wABI) via a minithyrotomy for medialization thyroplasty and evaluate its effect on a range of phonatory parameters using the excised larynx bench apparatus.
Study Design
Repeated measures with each larynx serving as its own control.
Methods
A prototype wABI was deployed in six excised canine larynges of various sizes through a minithyrotomy and then filled with saline. Mucosal wave, aerodynamic, and acoustic parameters were measured for three conditions: normal, vocal fold paralysis, and paralysis with the wABI.
Results
Phonation threshold pressure (P < .001), flow (P < .001), and power (P = .002) were significantly lower for wABI compared to paralysis trials; values did not differ significantly from normal trials. Percent jitter (P = .002) and percent shimmer (P = .007) were also significantly decreased compared to the paralysis condition, and values were not significantly different compared to normal. The mucosal wave was preserved after insertion of the wABI.
Conclusions
Effective vocal fold medialization with preservation of the mucosal wave was observed with the wABI in this preliminary excised larynx experiment. The wABI offers the potential for a minimally invasive insertion in addition to postoperative adjustability. Further studies in living animals and humans are warranted to evaluate clinical utility.
Level of Evidence
NA. Laryngoscope, 124:942-949, 2014
Details
- Title: Subtitle
- Excised larynx evaluation of wedge-shaped adjustable balloon implant for minimally invasive type I thyroplasty
- Creators
- Matthew R. Hoffman - University of Wisconsin School of Medicine and Public HealthErin E. Devine - University of Wisconsin–MadisonTimothy M. McCulloch - University of Wisconsin–MadisonJack J. Jiang - University of Wisconsin–Madison
- Resource Type
- Journal article
- Publication Details
- The Laryngoscope, Vol.124(4), pp.942-949
- Publisher
- Wiley
- DOI
- 10.1002/lary.24409
- PMID
- 24115091
- PMCID
- PMC4235617
- ISSN
- 0023-852X
- eISSN
- 1531-4995
- Number of pages
- 8
- Grant note
- F31 DC012495 / National Institute on Deafness and other Communicative Disorders; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Deafness & Other Communication Disorders (NIDCD) R01 DC008153 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA R33DC011130 / NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Deafness & Other Communication Disorders (NIDCD)
- Language
- English
- Date published
- 04/01/2014
- Academic Unit
- Otolaryngology
- Record Identifier
- 9984366276902771
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