Journal article
Exclusion of Usher syndrome gene from much of chromosome 4
Cytogenetic and genome research, Vol.50(2-3), pp.102-106
1989
DOI: 10.1159/000132733
PMID: 2776474
Abstract
Usher syndrome is an autosomal recessive disease characterized by dual sensory impairments; affected individuals are born with a sensorineural hearing loss and ultimately lose their sight as retinitis pigmentosa develops. Conventional protein markers previously tested in a Louisiana Acadian kindred suggested tentative linkage to vitamin D-binding protein on chromosome 4. DNA linkage studies do not confirm this linkage relationship and exclude much of chromosome 4 as the site of the Usher syndrome gene in these families.
Details
- Title: Subtitle
- Exclusion of Usher syndrome gene from much of chromosome 4
- Creators
- R.J.H SmithJ.D HolcombS.P DaigerC.T CaskeyM.Z PeliasB.R AlfordD.D FontenotJ.F Hejtmancik
- Resource Type
- Journal article
- Publication Details
- Cytogenetic and genome research, Vol.50(2-3), pp.102-106
- DOI
- 10.1159/000132733
- PMID
- 2776474
- NLM abbreviation
- Cytogenet Genome Res
- ISSN
- 1424-8581
- eISSN
- 1424-859X
- Publisher
- Basel, Switzerland
- Number of pages
- 5
- Language
- English
- Date published
- 1989
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Molecular Physiology and Biophysics; Anatomy and Cell Biology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Otolaryngology; Internal Medicine
- Record Identifier
- 9984006314102771
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