Journal article
Exclusion of close linkage of the dopamine transporter gene with schizophrenia spectrum disorders
The American journal of psychiatry, Vol.152(1), pp.134-136
01/1995
DOI: 10.1176/ajp.152.1.134
PMID: 7802105
Abstract
Involvement of genetic factors in the pathogenesis of schizophrenia spectrum disorders has been indicated in twin, adoption, and familial aggregation studies; the pivotal role played by the dopamine transporter in dopaminergic neurotransmission makes it a candidate gene for these disorders. Detection of close linkage between a dopamine transporter marker and schizophrenia spectrum disorders would strongly support the existence of causal relationships between genetic mutations at the dopamine transporter locus and the disease phenotype.
Details
- Title: Subtitle
- Exclusion of close linkage of the dopamine transporter gene with schizophrenia spectrum disorders
- Creators
- Antonio M Persico - From the Molecular Neurobiology Branch, National Institute on Drug Abuse/NIH, Baltimore, MD 21224Zhe Wu WangDonald W BlackNancy C AndreasenGeorge R UhlRaymond R Crowe
- Resource Type
- Journal article
- Publication Details
- The American journal of psychiatry, Vol.152(1), pp.134-136
- DOI
- 10.1176/ajp.152.1.134
- PMID
- 7802105
- NLM abbreviation
- Am J Psychiatry
- ISSN
- 0002-953X
- eISSN
- 1535-7228
- Publisher
- United States
- Grant note
- MH-00735 / NIMH NIH HHS MH-43212 / NIMH NIH HHS
- Language
- English
- Date published
- 01/1995
- Academic Unit
- Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003910102771
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