Journal article
Excretion of urinary volatile metabolites in response to alloxan induced diabetes of short duration in rats
Journal of chromatography. Biomedical applications, Vol.228(C), pp.33-42
03/12/1982
DOI: 10.1016/S0378-4347(00)80416-8
PMID: 7076757
Abstract
Alterations in urine volatile metabolites due to the induction of alloxan diabetes in the rat were examined by capillary gas chromatography and gas chromatography—mass spectrometry for the five days immediately following the onset of chronic hyperglycemia. Elevations of a number of metabolites were observed including several short chain ketones, acetophenone, 2-acetylfuran and indole. The value of urine volatile metabolic profiles as characteristic indicators of the diabetic condition is demonstrated through profiles obtained from a diabetic animal which spontaneously reverted to normal.
Details
- Title: Subtitle
- Excretion of urinary volatile metabolites in response to alloxan induced diabetes of short duration in rats
- Creators
- Gerald Rhodes - Indiana University BloomingtonMary L. Holland - Indiana University BloomingtonDonald Wiesler - Indiana University BloomingtonMilos NovotnýStephen A. MooreRichard G. Peterson - Indiana University School of Medicine - LafayetteDavid L. Felten
- Resource Type
- Journal article
- Publication Details
- Journal of chromatography. Biomedical applications, Vol.228(C), pp.33-42
- DOI
- 10.1016/S0378-4347(00)80416-8
- PMID
- 7076757
- NLM abbreviation
- J Chromatogr B Biomed Appl
- ISSN
- 0378-4347
- Publisher
- Elsevier B.V
- Number of pages
- 10
- Language
- English
- Date published
- 03/12/1982
- Academic Unit
- Pathology
- Record Identifier
- 9984047695702771
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