Journal article
Executive Summary: Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report
Chest, Vol.160(6), pp.2247-2259
12/2021
DOI: 10.1016/j.chest.2021.07.056
PMID: 34352279
Abstract
This is the 2nd update to the 9th edition of these guidelines. We provide recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions, four of which have not been addressed previously.
We generate strong and weak recommendations based on high-, moderate-, and low-certainty evidence, using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodology.
The panel generated 29 guidance statements, 13 of which are graded as strong recommendations, covering aspects of antithrombotic management of VTE from initial management through secondary prevention and risk reduction of postthrombotic syndrome. Four new guidance statements have been added that did not appear in the 9th edition (2012) or 1st update (2016). Eight statements have been substantially modified from the 1st update.
New evidence has emerged since 2016 that further informs the standard of care for patients with VTE. Substantial uncertainty remains regarding important management questions, particularly in limited disease and special patient populations.
Details
- Title: Subtitle
- Executive Summary: Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report
- Creators
- Scott M Stevens - Intermountain HealthcareScott C Woller - Intermountain HealthcareLisa Baumann Kreuziger - Medical College of WisconsinHenri Bounameaux - University of GenevaKevin Doerschug - University of IowaGeert-Jan Geersing - Utrecht UniversityMenno V Huisman - Leiden University Medical CenterClive Kearon - McMaster UniversityChristopher S King - Inova Fairfax HospitalAndrew J Knighton - Intermountain HealthcareErica Lake - Essentia Institute of Rural Health, Duluth, MNSusan Murin - University of California, DavisJanine R.E Vintch - UCLA Medical CenterPhilip S Wells - Ottawa HospitalLisa K Moores - Uniformed Services University of the Health Sciences
- Resource Type
- Journal article
- Publication Details
- Chest, Vol.160(6), pp.2247-2259
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.chest.2021.07.056
- PMID
- 34352279
- ISSN
- 0012-3692
- eISSN
- 1931-3543
- Grant note
- DOI: 10.13039/100009965, name: American College of Physicians
- Language
- English
- Date published
- 12/2021
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Hardin Library; Internal Medicine
- Record Identifier
- 9984248829402771
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