Expanding Genetic Code Expansion through Resource Facilities, Workshops, and Conferences

E. James Petersson; Ryan A Mehl; Christopher A Ahern

doi:10.3390/ijms20092103

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Expanding Genetic Code Expansion through Resource Facilities, Workshops, and Conferences

Journal article

Open access

Peer reviewed

Expanding Genetic Code Expansion through Resource Facilities, Workshops, and Conferences

E. James Petersson, Ryan A Mehl and Christopher A Ahern

International journal of molecular sciences, Vol.20(9), p.2103

05/01/2019

DOI: 10.3390/ijms20092103

PMCID: PMC6539083

PMID: 31035437

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Abstract

Genetic Code Expansion (GCE) enables the encoding of amino acids with diverse chemical properties. This approach has tremendous potential to advance biological discoveries in basic research, medical, and industrial settings. Given the multiple technical approaches and the associated research activities used to achieve GCE, herein we have taken the opportunity to describe ongoing out-reach efforts in the GCE community. These include Resource Facilities that nucleate expertise and reagents within a specific GCE discipline, hands-on Workshops to provide GCE training, and GCE Conferences which bring the community together in a collegial setting. The overall goal of these activities is to accelerate the integration of GCE approaches into more research settings and to facilitate solutions to common technical hurdles.

non-canonical amino acid

genetic code expansion

unnatural amino acid

amber suppression

Conference Report

Details

Title: Subtitle: Expanding Genetic Code Expansion through Resource Facilities, Workshops, and Conferences
Creators: E. James Petersson - Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104-6323, USA
Ryan A Mehl - Department of Biochemistry and Biophysics, Oregon State University, 2011 Ag Life Sciences Building, Corvallis, OR 97331, USA
Christopher A Ahern - Department of Molecular Physiology and Biophysics, The University of Iowa, 4270 Carver Biomedical Research Building, 285 Newton Road, Iowa City, IA 52242, USA
Resource Type: Journal article
Publication Details: International journal of molecular sciences, Vol.20(9), p.2103
DOI: 10.3390/ijms20092103
PMID: 31035437
PMCID: PMC6539083
NLM abbreviation: Int J Mol Sci
ISSN: 1422-0067
eISSN: 1422-0067
Publisher: MDPI
Language: English
Date published: 05/01/2019
Academic Unit: Molecular Physiology and Biophysics; Iowa Neuroscience Institute
Record Identifier: 9984070715302771

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