Expansion of a Haematoma after Urokinase Thrombolysis of Superior Sagittal Sinus Thrombosis

C.J Moran; D.-W.T Cross; C.P Derdeyn; A.W Dromerick; R.G Dacey

doi:10.1177/159101999700300108

Back

Expansion of a Haematoma after Urokinase Thrombolysis of Superior Sagittal Sinus Thrombosis

Journal article

Peer reviewed

Expansion of a Haematoma after Urokinase Thrombolysis of Superior Sagittal Sinus Thrombosis

C.J Moran, D.-W.T Cross, C.P Derdeyn, A.W Dromerick and R.G Dacey

Interventional neuroradiology, Vol.3(1), pp.81-86

03/1997

DOI: 10.1177/159101999700300108

PMID: 20678374

View Online

Abstract

Thrombosis of the superior sagittal sinus may result in significant morbidity and recently up to 20% mortality. Primary treatment has consisted of anticoagulation and methods for controlling increased intracranial pressure. The development of interventional neuroradiologic techniques has enabled infusion of thrombolytics at the clot. We describe a woman with a cerebral haemorrhage due to a thrombosed superior sagittal sinus. Her decreased level of consciousness and increasing hemiparesis prompted direct thrombolytic therapy (urokinase). Flow was restored in the occluded sinus, but an acute expansion of the haematoma an hour after conclusion of the infusion resulted in temporary worsening of her neurologic deficits. Although the ultimate outcome was satisfactory, the possibility of further intracranial bleeding must be balanced against the risk of death with conservative therapy.

venous

thrombolysis

interventional neuroradiology

thrombosis

superior sagittal sinus

urokinase

Details

Title: Subtitle: Expansion of a Haematoma after Urokinase Thrombolysis of Superior Sagittal Sinus Thrombosis
Creators: C.J Moran - Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine; St. Louis, Missouri
D.-W.T Cross - Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine; St. Louis, Missouri
C.P Derdeyn - Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine; St. Louis, Missouri
A.W Dromerick - Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine; St. Louis, Missouri
R.G Dacey - Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine; St. Louis, Missouri
Resource Type: Journal article
Publication Details: Interventional neuroradiology, Vol.3(1), pp.81-86
Publisher: SAGE Publications; London, England
DOI: 10.1177/159101999700300108
PMID: 20678374
ISSN: 1591-0199
eISSN: 2385-2011
Language: English
Date published: 03/1997
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984020998502771

Metrics

23 Record Views