Journal article
Experience with Peroral Endoscopic Myotomy for Achalasia and Spastic Esophageal Motility Disorders at a Tertiary U.S. Center
Clinical endoscopy, Vol.53(3), pp.321-327
05/01/2020
DOI: 10.5946/ce.2019.110
PMCID: PMC7280846
PMID: 31744270
Abstract
Background/Aims: Peroral endoscopic myotomy (POEM) is a novel procedure for the treatment of achalasia and spastic esophageal disorders. Experience with POEM is limited, but its reported outcomes are excellent. It is deemed safe even for patients with prior interventions.
Methods: This retrospective review included patients who underwent POEM at a tertiary US center. POEM was performed in a multidisciplinary approach by advanced endoscopists and foregut surgeons. Clinical success was defined as a post-POEM Eckardt score <= 3.
Results: A total of 125 patients were included. Median follow-up period was 18 months (interquartile range, 10-22 months). Clinical success was achieved in 92% of patients and persisted at 12 months in 88% of patients. Mucosal barrier failure (MBF) occurred in 7 patients, 2 of whom required surgical intervention. MBF was more common in patients with prior laparoscopic Heller myotomy (19% vs. 3%, p=0.015). MBF requiring surgical intervention occurred early in the learning curve.
Conclusions: POEM is safe and effective in the treatment of achalasia and spastic esophageal disorders even after failed prior interventions.
Details
- Title: Subtitle
- Experience with Peroral Endoscopic Myotomy for Achalasia and Spastic Esophageal Motility Disorders at a Tertiary U.S. Center
- Creators
- Maen Masadeh - University of Iowa Hospitals and ClinicsPeter Nau - University of Iowa Hospitals and ClinicsSubhash Chandra - University of Iowa Hospitals and ClinicsJagpal Klair - University of IowaJohn Keech - University of Iowa Hospitals and ClinicsKalpaj Parekh - University of Iowa Hospitals and ClinicsRami El Abiad - University of Iowa Hospitals and ClinicsHenning Gerke - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Clinical endoscopy, Vol.53(3), pp.321-327
- DOI
- 10.5946/ce.2019.110
- PMID
- 31744270
- PMCID
- PMC7280846
- NLM abbreviation
- Clin Endosc
- ISSN
- 2234-2400
- eISSN
- 2234-2443
- Publisher
- Korean Soc Gastrointestinal Endoscopy
- Number of pages
- 7
- Language
- English
- Date published
- 05/01/2020
- Academic Unit
- Anatomy and Cell Biology; Gastroenterology and Hepatology; Surgery; Cardiothoracic Surgery; Internal Medicine
- Record Identifier
- 9984284454502771
Metrics
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