Journal article
Experiences of BRCA1/2 Gene Mutation-Positive Women With Cancer in Communicating Genetic Risk to Their Relatives
Cancer nursing, Vol.44(3), pp.E142-E150
05/01/2021
DOI: 10.1097/NCC.0000000000000796
PMID: 32022782
Abstract
Background
When a woman is diagnosed with hereditary breast or ovarian cancer, family members may be at high risk of cancers associated with BRCA1/2 gene mutation and benefit from disclosure of the genetic test result. This duty of informing relatives may be distressing, or relatives may not be properly informed. Objective
To qualitatively describe breast cancer patients' experiences communicating genetic risk of cancer to their relatives. Methods
Probands with BRCA1/2 gene mutations were recruited from an oncology institute in Istanbul, Turkey, and interviewed by telephone. Qualitative content analysis was conducted to derive central elements of the 30 women's experiences communicating genetic risk to their relatives. Results
Six themes were identified: response to genetic test results, reason for communication, feelings about communication, reflection after communication, results of communication, and needs. Conclusion
Women with cancer found to have BRCA1/2 gene mutations tended to share their genetic test results within the family. The main motives for sharing test results were the desire to encourage relatives to get tested and moral and ethical convictions. Women needed explicit information regarding cancer risk and risk-reducing strategies to act upon. Implications for Practice
The women's feelings and reflections about the communication process were varied and suggest that personalized genetic risk communication interventions may better support women with BRCA1/2 gene mutations during and after communication with relatives. Long-term follow-up of those women is essential because of the need for informed decision on risk-reducing strategies.
Details
- Title: Subtitle
- Experiences of BRCA1/2 Gene Mutation-Positive Women With Cancer in Communicating Genetic Risk to Their Relatives
- Creators
- Memnun Seven - Istanbul UniversityLisa L. Shah - University of PittsburghSandra Daack-Hirsch - Univ Iowa, Coll Nursing, Iowa City, IA 52242 USAHulya Yazici - Istanbul University
- Resource Type
- Journal article
- Publication Details
- Cancer nursing, Vol.44(3), pp.E142-E150
- Publisher
- Lippincott Williams & Wilkins
- DOI
- 10.1097/NCC.0000000000000796
- PMID
- 32022782
- ISSN
- 0162-220X
- eISSN
- 1538-9804
- Number of pages
- 9
- Grant note
- T32NR0097590 / National Institutes of Health/National Institute of Nursing Research T32 postdoctoral fellowship European Oncology Nursing Society
- Language
- English
- Date published
- 05/01/2021
- Academic Unit
- Nursing; Fraternal Order of Eagles Diabetes Research Center; Public Policy Center (Archive)
- Record Identifier
- 9984283850902771
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