Experimental dissociation of behavioral and cardiovascular outcome in the borderline hypertensive rat

Richard J Viken; Alan Kim Johnson; Brian Murray

doi:10.1016/0031-9384(90)90286-D

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Experimental dissociation of behavioral and cardiovascular outcome in the borderline hypertensive rat

Journal article

Peer reviewed

Experimental dissociation of behavioral and cardiovascular outcome in the borderline hypertensive rat

Richard J Viken, Alan Kim Johnson and Brian Murray

Physiology & behavior, Vol.48(1), pp.203-205

1990

DOI: 10.1016/0031-9384(90)90286-D

PMID: 2236272

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Abstract

F 1 Offspring of hypertensive and normotensive rats (BHR) were reared with either hypertensive (SHR) or normotensive (WKY) cagemates, and observations were conducted at two developmental periods to assess the effects of rearing condition on the social environment and the behavior of BHR subjects. SHR displayed significantly more agonistic behavior during development than WKY, and BHR subjects reared with SHR were the targets of significantly more agonistic behavior than BHR subjects reared with WKY cagemates. BHR reared with SHR initiated twice as much agonistic behavior as BHR reared with WKY. When heart rate and blood pressure were assessed at 75–80 days of age, however, neither the alterations in developmental social environment nor the alterations in the behavioral characteristics of BHR were associated with differences in cardiovascular variables. The results do not support a causal connection between behavioral characteristics and cardiovascular outcome.

Agonistic behavior

Blood pressure

Borderline hypertensive rats

Social development

Spontaneously hypertensive rats

Details

Title: Subtitle: Experimental dissociation of behavioral and cardiovascular outcome in the borderline hypertensive rat
Creators: Richard J Viken - Department of Psychology, Indiana University, Bloomington, IN 47405 USA
Alan Kim Johnson - Pharmacology Cardiovascular Center, University of Iowa, Iowa City, IA 52242 USA
Brian Murray - Department of Psychology, University of Iowa, Iowa City, IA 52242 USA
Resource Type: Journal article
Publication Details: Physiology & behavior, Vol.48(1), pp.203-205
DOI: 10.1016/0031-9384(90)90286-D
PMID: 2236272
NLM abbreviation: Physiol Behav
ISSN: 0031-9384
eISSN: 1873-507X
Publisher: Elsevier Inc
Language: English
Date published: 1990
Academic Unit: Psychological and Brain Sciences; Neuroscience and Pharmacology; Health, Sport, and Human Physiology
Record Identifier: 9984213413702771

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