Journal article
Experimental occlusion of the central artery of the retina. IV: Retinal tolerance time to acute ischaemia
British journal of ophthalmology, Vol.64(11), pp.818-825
11/1980
DOI: 10.1136/bjo.64.11.818
PMCID: PMC1043826
PMID: 7426553
Abstract
Ophthalmoscopic, fluorescein angiographic, electrophysiological, and morphological studies on 63 eyes of rhesus monkeys with acute transient experimental occlusion of the central artery of the retina (OCAR) showed that the retina suffered irreparable damage after ischaemia of 105 minutes but recovered well after ischaemia of 97-98 minutes. The tolerance time of the brain to acute transient ischaemia is many times shorter than that of the retina. The metabolism of ischaemic neurones (in the retina and brain) is discussed with a view to explaining this difference, and also the various factors possibly responsible for the retina's longer tolerance to ischaemia, as compared to the brain.
Details
- Title: Subtitle
- Experimental occlusion of the central artery of the retina. IV: Retinal tolerance time to acute ischaemia
- Creators
- S S HayrehT A Weingeist
- Resource Type
- Journal article
- Publication Details
- British journal of ophthalmology, Vol.64(11), pp.818-825
- DOI
- 10.1136/bjo.64.11.818
- PMID
- 7426553
- PMCID
- PMC1043826
- ISSN
- 0007-1161
- eISSN
- 1468-2079
- Grant note
- EY-01576 / NEI NIH HHS
- Language
- English
- Date published
- 11/1980
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984182762802771
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