Experimental research on the genotoxicity of various root canal antiseptics in the SOS chromotest

W Klimm; S Janz; A Gabert

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Journal article

Experimental research on the genotoxicity of various root canal antiseptics in the SOS chromotest

W Klimm, S Janz and A Gabert

Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt, Vol.77(2), pp.128-130

1989

PMID: 2526434

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Abstract

The genotoxicity of the endodontic antiseptics chlorhexidine digluconate, chloramine and sodium hypochlorite was determined by SOS chromotest using Bioscreen Analyzer Systems (Labsystem OY). All antiseptics did not show a genotoxic effect. Chlorhexidine digluconate was the most efficient antimicrobial agent against E. coli PQ 37.

DNA Repair - drug effects

Escherichia coli - drug effects

Root Canal Irrigants - toxicity

Mutagenicity Tests - methods

SOS Response (Genetics) - drug effects

Anti-Infective Agents, Local

DNA, Bacterial - drug effects

Mutagenicity Tests - instrumentation

Details

Title: Subtitle: Experimental research on the genotoxicity of various root canal antiseptics in the SOS chromotest
Creators: W Klimm
S Janz
A Gabert
Resource Type: Journal article
Publication Details: Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt, Vol.77(2), pp.128-130
PMID: 2526434
ISSN: 0303-6464
Alternative title: Experimentelle Untersuchungen zur Genotoxizität verschiedener Wurzelkanalantiseptika im SOS-Chromotest
Language: German
Date published: 1989
Academic Unit: Pathology
Record Identifier: 9984083216102771

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