Expert consensus on bedside transcatheter closure of patent ductus arteriosus in extremely low birth weight infants

Peter Ewert; Patrick J McNamara; Lee Benson; Charles C Roehr; Sophie Malekzadeh-Milani; Alain Fraisse; Bert Albers; Evan Zahn; Sven Wellmann

doi:10.1038/s41390-026-04977-7

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Expert consensus on bedside transcatheter closure of patent ductus arteriosus in extremely low birth weight infants

Journal article

Open access

Peer reviewed

Expert consensus on bedside transcatheter closure of patent ductus arteriosus in extremely low birth weight infants

Peter Ewert, Patrick J McNamara, Lee Benson, Charles C Roehr, Sophie Malekzadeh-Milani, Alain Fraisse, Bert Albers, Evan Zahn and Sven Wellmann

Pediatric research

07/16/2026

DOI: 10.1038/s41390-026-04977-7

PMID: 42463802

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Abstract

Transcatheter closure is becoming the standard of care for definitive closure of patent ductus arteriosus (PDA) in premature infants. To avoid risks associated with the transportation of a fragile neonate, the intervention can be performed as a bedside procedure within the neonatal intensive care unit, even in extremely low birth weight (ELBW) infants. Limited evidence-based guidelines are available for transcatheter PDA closure in premature infants in general and for bedside PDA closure specifically. This framework represents an expert consensus regarding bedside PDA closure in ELBW infants and guidance for procedural implementation. Recommendations for patient eligibility, pre-procedural planning, staff requirements, procedural aspects, imaging and follow-up and a stepwise implementation plan for a bedside PDA closure program are presented. IMPACT: Extremely low birth weight (ELBW) infants with a patent ductus arteriosus (PDA) may be considered for transcatheter PDA closure. An expert consensus is provided on bedside transcatheter PDA closure performed within the neonatology intensive care unit, thereby mitigating the risks associated with transportation of these highly vulnerable infants outside of the neonatology intensive care unit. Guidance is provided regarding procedural aspects, including staff requirements, planning, setting, and imaging, and implementation of a bedside transcatheter PDA closure program.

Details

Title: Subtitle: Expert consensus on bedside transcatheter closure of patent ductus arteriosus in extremely low birth weight infants
Creators: Peter Ewert - Deutsches Herzzentrum München
Patrick J McNamara - University of Iowa
Lee Benson - University of Toronto
Charles C Roehr - North Bristol NHS Trust
Sophie Malekzadeh-Milani - Hôpital Necker-Enfants Malades
Alain Fraisse - Royal Brompton & Harefield NHS Foundation Trust
Bert Albers - Streekziekenhuis Koningin Beatrix
Evan Zahn - Cedars-Sinai Smidt Heart Institute
Sven Wellmann - University of Regensburg
Resource Type: Journal article
Publication Details: Pediatric research
DOI: 10.1038/s41390-026-04977-7
PMID: 42463802
NLM abbreviation: Pediatr Res
ISSN: 1530-0447
eISSN: 1530-0447
Publisher: Springer Nature
Grant note: Abbott
For this work, Abbott provided funding for manuscript preparation and writing services. There was no involvement from industry regarding the content of the manuscript. Open Access funding enabled and organized by Projekt DEAL.
Language: English
Electronic publication date: 07/16/2026
Academic Unit: Stead Family Department of Pediatrics; Neonatology
Record Identifier: 9985183395102771

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