Journal article
Experts Achieve Consensus on a Majority of Statements Regarding Platelet Rich Plasma Treatments for Treatment of Musculoskeletal Pathology
Arthroscopy, Vol.40(2), pp.470-477.e1
02/2024
DOI: 10.1016/j.arthro.2023.08.020
PMID: 37625660
Abstract
PURPOSE The purpose of this study was to establish consensus statements on platelet-rich plasma (PRP) for the treatment of musculoskeletal pathologies. METHODS A consensus process on the treatment of PRP utilizing a modified Delphi technique was conducted. Thirty-five orthopaedic surgeons and sports medicine physicians participated in these consensus statements on PRP. The participants were composed of representatives of the Biologic Association, representing nine international orthopedic and musculoskeletal professional societies invited due to their active interest in the study of orthobiologics. Consensus was defined as achieving 80-89% agreement, strong consensus was defined as 90-99% agreement, and unanimous consensus was indicated by 100% agreement with a proposed statement. RESULTS There was consensus on 62% of statements about PRP. CONCLUSION(1) PRP should be classified based on platelet count, leukocyte count, red blood count, activation method, and pure-plasma vs. fibrin matrix, (2) PRP characteristics for reporting in research studies are platelet count, leukocyte count, neutrophil count, red blood cell count, total volume, the volume of injection, delivery method, and the number of injections, (3) the prognostic factors for those undergoing PRP injections are age, BMI, severity/grade of pathology, chronicity of pathology, prior injections and response, primary diagnosis (primary vs. post-surgery vs. post-trauma vs. psoriatic), comorbidities, and smoking, (4) regarding age and BMI, there is no minimum or maximum, but clinical judgment should be used at extremes of either, (5) the ideal dose of PRP is undetermined, and (6) the minimal volume required is unclear and may depend on the pathology.
Details
- Title: Subtitle
- Experts Achieve Consensus on a Majority of Statements Regarding Platelet Rich Plasma Treatments for Treatment of Musculoskeletal Pathology
- Creators
- Eoghan T HurleySeth L ShermanDaniel J StokesScott A RodeoShane A ShapiroKen MautnerDon A BufordJason L DragooBert R MandelbaumKenneth R ZaslavBrian J ColeRachel M FrankMukesh AhujaAdam W AnzJorge ChahlaConstance R ChuRamon CugatJoao Espregueira-MendesJack FarrDavid C FlaniganAlberto GobbiAndreas H GomollDaniel A GrandeMederic M HallKay HorschJason L KohElizaveta KonChristian LattermannLouis F McIntyreIain R MurrayGeorge F MuschlerNorimasa NakamuraSurena NamdariNicolas S PiuzziDaniel B F SarisNicholas A SgaglioneKurt P SpindlerJohn M TokishAdam B Yanke
- Resource Type
- Journal article
- Publication Details
- Arthroscopy, Vol.40(2), pp.470-477.e1
- DOI
- 10.1016/j.arthro.2023.08.020
- PMID
- 37625660
- ISSN
- 0749-8063
- eISSN
- 1526-3231
- Language
- English
- Electronic publication date
- 08/23/2023
- Date published
- 02/2024
- Academic Unit
- Radiology; Orthopedics and Rehabilitation; Family and Community Medicine
- Record Identifier
- 9984459414902771
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